Hsp72 Is an Intracellular Target of the α,β-Unsaturated Sesquiterpene Lactone, Parthenolide
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DOI: 10.1021/acsomega.7b00954
Abstract: The electrophilic natural product parthenolide has generated significant interest as a model for potential chemotherapeutics. Similar to other α,β-unsaturated carbonyl electrophiles, parthenolide induces the heat shock response in leukemia cells, potentially through covalent adduction of… read more here.
Keywords: heat shock; parthenolide; parthenolide derivative; hsp72 ... See more keywords