SR 57227A is a partial agonist/partial antagonist of 5-HT3 receptor and inhibits subsequent 5-HT- or SR 57227A-induced 5-HT3 receptor current.
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DOI: 10.1016/j.bbrc.2018.11.174
Abstract: The serotonin (5-hydroxytryptamine) type 3 (5-HT3) receptors are transmembrane ligand-gated ion channels. Although several 5-HT3 receptor agonists have been used as preclinical tools, SR 57227A is the most commonly used 5-HT3 receptor agonist with the… read more here.
Keywords: agonist partial; partial antagonist; ht3 receptor; receptor ... See more keywords