The histopathological and pharmacodynamic effects of intradetrusor decorin injected in a rabbit partial bladder outlet obstruction model
Sign Up to like & getrecommendations! Published in 2017 at "International Urology and Nephrology"
DOI: 10.1007/s11255-017-1518-x
Abstract: Purpose To evaluate whether or not the bladder function can be protected by supporting the detrusor with decorin levels during the fibrotic process.MethodsForty-two male rabbits were divided into three main groups, partial bladder outlet obstruction… read more here.
Keywords: bladder; intradetrusor decorin; partial bladder; outlet obstruction ... See more keywords
Mesenchymal stem cell therapy inhibited inflammatory and profibrotic pathways induced by partial bladder outlet obstruction and prevented high-pressure urine storage.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pediatric urology"
DOI: 10.1016/j.jpurol.2019.03.003
Abstract: BACKGROUND Partial bladder outlet obstruction (pBOO) is characterized by an initial inflammatory response that progresses to smooth muscle hypertrophy and fibrosis. Current treatment modalities carry high risk of morbidity. Mesenchymal stem cells (MSCs) are undifferentiated adult… read more here.
Keywords: partial bladder; therapy; bladder outlet; outlet obstruction ... See more keywords
Survivin (BIRC5) regulates bladder fibrosis in a rat model of partial bladder outlet obstruction
Sign Up to like & getrecommendations! Published in 2022 at "Chinese Medical Journal"
DOI: 10.1097/cm9.0000000000002022
Abstract: To the Editor: Fibrosis is a long duration wound healing process triggered by complex cellular and molecular responses that contributes to tissue or organ reconstruc-tion. [1] Bladder fi brosis is initiated by pathological pressure such… read more here.
Keywords: bladder outlet; bladder; outlet obstruction; partial bladder ... See more keywords
Anti-fibrotic effect of tocotrienols for bladder dysfunction due to partial bladder outlet obstruction
Sign Up to like & getrecommendations! Published in 2023 at "Investigative and Clinical Urology"
DOI: 10.4111/icu.20220328
Abstract: Purpose To investigate potential beneficial effects of tocotrienols which have been suggested to inhibit hypoxia-inducible factor (HIF) pathway, on partial bladder outlet obstruction (PBOO)-induced bladder pathology. Materials and Methods PBOO was surgically created in juvenile… read more here.
Keywords: bladder outlet; bladder; outlet obstruction; pboo ... See more keywords