Increased Dissociation of Adamantanamines in Influenza A M2 S31N with Partial Block by Rimantadine.
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DOI: 10.1016/j.bpj.2020.09.015
Abstract: The ubiquitous mutation from serine (WT) to asparagine at residue 31 (S31N) in the influenza A M2 channel renders it insensitive to amantadine (AMT) and rimantadine (RMT) block, but it is unknown whether the inhibition… read more here.
Keywords: partial block; rmt; block; dissociation ... See more keywords