Hydroxy Cinnamic Acid Derivatives as Partial PPARγ Agonists: In silico Studies, Synthesis and Biological Characterization Against Chronic Myeloid Leukemia Cell Line (K562).
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DOI: 10.2174/1871520616666160607010156
Abstract: BACKGROUND Peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear receptor that regulates the expression of many genes relevant to carcinogenesis. By analogy to selective estrogen receptor modulator for treatment of cancer, selective or partial PPARγ… read more here.
Keywords: ppar; ppar agonists; acid derivatives; partial ppar ... See more keywords