Basic coagulation tests as surrogates of dabigatran levels in a pre-operative setting: Analysis of five activated partial thromboplastin time reagents and thrombin time.
Sign Up to like & getrecommendations! Published in 2018 at "Thrombosis research"
DOI: 10.1016/j.thromres.2018.09.051
Abstract: BACKGROUND In patients who are receiving dabigatran, a direct oral anticoagulant, measuring the anticoagulant effect before surgery may be needed in certain circumstances. Although the dilute thrombin time (dTT) can reliably measure dabigatran levels, it… read more here.
Keywords: coagulation tests; time; thrombin time; activated partial ... See more keywords
SUBSEQUENT CHANGES IN DOSING REQUIREMENTS TO PRODUCE THERAPEUTIC ANTICOAGULATION WITH INJECTABLE DIRECT THROMBIN INHIBITORS AFTER INSTITUTIONAL CHANGE TO THE ACTIVATED PARTIAL THROMBOPLASTIN TIME REAGENT
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(18)32645-7
Abstract: Injectable direct thrombin inhibitors (iDTI) argatroban and bivalirudin are useful in the management of patients with documented or suspected heparin induced thrombocytopenia (HIT). Management of iDTIs includes monitoring with the activated partial thromboplastin time (aPTT)… read more here.
Keywords: thromboplastin time; direct thrombin; injectable direct; thrombin inhibitors ... See more keywords
An Analysis of the Sensitivity of the Activated Partial Thromboplastin Time (APTT) Assay, as Used in a Large Laboratory Network, to Coagulation Factor Deficiencies.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of clinical pathology"
DOI: 10.1093/ajcp/aqac013
Abstract: OBJECTIVES To advance knowledge in using the ex vivo method to identify factor sensitivity of the activated partial thromboplastin time (APTT), using data from a hemophilia and reference hemostasis laboratory; to evaluate application of inclusion… read more here.
Keywords: laboratory; sensitivity; activated partial; partial thromboplastin ... See more keywords
Activated Partial Thromboplastin Time versus Anti-Factor Xa Levels for Monitoring Unfractionated Heparin Therapy in Children: An Institutional Experience
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pediatric Hematology/Oncology"
DOI: 10.1097/mph.0000000000000966
Abstract: To the Editor: Epidemiologic studies from Canada and the Netherlands estimated the incidence of venous thrombo-embolism (VTE) to be 0.07 to 0.14/10,000 children (and neonates), respectively.1,2 A recent study, however, has indicated a 70% increase… read more here.
Keywords: heparin; thromboplastin time; partial thromboplastin; unfractionated heparin ... See more keywords
Unexpected, isolated activated partial thromboplastin time prolongation: A practical mini‐review
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Haematology"
DOI: 10.1111/ejh.13394
Abstract: A common inquiry in coagulation laboratories is how to interpret an unexpected, isolated prolonged activated partial thromboplastin time (APTT). In this context, isolated means together with a normal prothrombin time (PT) and/or normal international normalized… read more here.
Keywords: thromboplastin time; time; isolated prolonged; partial thromboplastin ... See more keywords
Effect of dual versus mono antiplatelet therapy on recurrent stroke modulated by activated partial thromboplastin time
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Neurology"
DOI: 10.1111/ene.13961
Abstract: The efficacy of dual antiplatelet treatment may be modified by many factors. The aim was to assess whether the effect of clopidogrel plus aspirin versus aspirin alone on recurrent stroke would be affected by admission… read more here.
Keywords: thromboplastin time; antiplatelet; recurrent stroke; effect ... See more keywords
Activated Partial Thromboplastin Time and Mortality in Coronary Artery Bypass Grafting Patients
Sign Up to like & getrecommendations! Published in 2022 at "Disease Markers"
DOI: 10.1155/2022/2918654
Abstract: Background To evaluate the prognostic value of preoperative activated partial thromboplastin time (APTT) in patients who underwent coronary artery bypass grafting (CABG). Methods All data were extracted from the Medical Information Mart for Intensive Care… read more here.
Keywords: thromboplastin time; year; activated partial; partial thromboplastin ... See more keywords
The missing slope: paradoxical shortening of activated partial thromboplastin time in a patient on unfractionated heparin therapy
Sign Up to like & getrecommendations! Published in 2021 at "Biochemia Medica"
DOI: 10.11613/bm.2021.021003
Abstract: This case report describes false shortening of activated partial thromboplastin time (aPTT) due to erroneous optical reading of the clotting point in the presence of unfractionated heparin (UFH), and a biphasic waveform. Activated partial thromboplastin… read more here.
Keywords: therapy; time; partial thromboplastin; activated partial ... See more keywords
Evaluation of Antifactor-Xa Heparin Assay and Activated Partial Thromboplastin Time Values in Patients on Therapeutic Continuous Infusion Unfractionated Heparin Therapy
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DOI: 10.1177/1076029619876030
Abstract: Clinical uncertainty exists regarding which assay should be designated as the standard monitoring coagulation test for intravenous unfractionated heparin (UFH). Several studies have compared the use of activated partial thromboplastin time (aPTT) and antifactor-Xa (anti-Xa)… read more here.
Keywords: heparin; thromboplastin time; heparin assay; partial thromboplastin ... See more keywords
Standardization of Coagulation Factor V Reference Intervals, Prothrombin Time, and Activated Partial Thromboplastin Time in Mice for Use in Factor V Deficiency Pathological Models
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2022.846216
Abstract: Factor V together with activated factor X forms the prothrombinase complex, which transforms prothrombin into thrombin. The Mus musculus species is characterized by very high levels of this factor and short clotting times, which hinders… read more here.
Keywords: time; prothrombin time; partial thromboplastin; activated partial ... See more keywords
Genetic Polymorphisms Associated with Prothrombin Time and Activated Partial Thromboplastin Time in Chinese Healthy Population
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DOI: 10.3390/genes13101867
Abstract: (1) Background: The purpose of this study was to evaluate the effect of gene polymorphisms on prothrombin time (PT) and activated partial thromboplastin time (APTT) in a healthy Chinese population. (2) Methods: A total of… read more here.
Keywords: thromboplastin time; time; activated partial; time activated ... See more keywords