Chronic partial TrkB activation reduces seizures and mortality in a mouse model of Dravet syndrome
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DOI: 10.1073/pnas.2022726119
Abstract: Significance Dravet syndrome (DS) is a severe childhood epileptic encephalopathy characterized by intractable seizures and comorbidities, including a high rate of premature mortality. DS is mainly caused by loss-of-function mutations of the Scn1a gene encoding… read more here.
Keywords: function; trkb receptor; mortality; dravet syndrome ... See more keywords