In vitro and in silico testing of partially and fully bioresorbable vascular scaffold.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of biomechanics"
DOI: 10.1016/j.jbiomech.2020.110158
Abstract: Coronary artery disease (CAD), one of the leading causes of death globally, occurs due to the growth of atherosclerotic plaques in the coronary arteries, causing lesions which restrict the flow of blood to the myocardium.… read more here.
Keywords: silico testing; vitro silico; testing partially; fully bioresorbable ... See more keywords
Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo
Sign Up to like & getrecommendations! Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky037
Abstract: Abstract Small interfering RNA (siRNA)-based drugs require chemical modifications or formulation to promote stability, minimize innate immunity, and enable delivery to target tissues. Partially modified siRNAs (up to 70% of the nucleotides) provide significant stabilization… read more here.
Keywords: fully chemically; mediated delivery; delivery; chemically modified ... See more keywords