Super-heated aqueous particle engineering (SHAPE): a novel method for the micronization of poorly water soluble drugs
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pharmaceutical Investigation"
DOI: 10.1007/s40005-017-0368-y
Abstract: Super-heated aqueous particle engineering (SHAPE) is a novel particle engineering technology that utilizes the elevated boiling point of pressurized water in order to melt and emulsify hydrophobic drug particles, and then use the newly formed… read more here.
Keywords: engineering; particle engineering; shape; drug ... See more keywords
Particle Engineering of Gypsum Through Templating with Starch
Sign Up to like & getrecommendations! Published in 2021 at "Industrial & Engineering Chemistry Research"
DOI: 10.1021/acs.iecr.1c00032
Abstract: The conversion of CaSO4·0.5H2O to CaSO4·2H2O (gypsum) is of great importance industrially, being the reaction behind plasterboard production and the setting of medical plasters. This hydration proc... read more here.
Keywords: engineering; gypsum; templating starch; particle engineering ... See more keywords
Microfluidic Particle Engineering of Hydrophobic Drug with Eudragit E100─Bridging the Amorphous and Crystalline Gap.
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DOI: 10.1021/acs.molpharmaceut.2c00714
Abstract: Co-processing active pharmaceutical ingredients (APIs) with excipients is a promising particle engineering technique to improve the API physical properties, which can lead to more robust downstream drug product manufacturing and improved drug product attributes. Excipients… read more here.
Keywords: eudragit e100; neat api; particle engineering; amorphous crystalline ... See more keywords
Particle engineering by optimization for the unseeded batch cooling crystallization of L-asparagine monohydrate
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DOI: 10.1039/c7ce01291h
Abstract: Due to the stochastic nature of the nucleation event, producing the desired crystal size distribution (CSD) consistently is a challenging task in an unseeded crystallization process. A predictive dynamic model based on a population balance… read more here.
Keywords: unseeded batch; optimization; particle engineering; crystallization ... See more keywords