Articles with "particle induced" as a keyword



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Expression of XBP1s in fibroblasts is critical for TiAl6V4 particle‐induced RANKL expression and osteolysis

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Published in 2017 at "Journal of Orthopaedic Research"

DOI: 10.1002/jor.23056

Abstract: Wear particle‐induced osteolysis is a major cause of aseptic loosening, which is one of the most common reasons for total hip arthroplasty (THA) failure. Previous studies have shown that the expression of Receptor activation of… read more here.

Keywords: xbp1s; particle induced; osteolysis; expression ... See more keywords
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Ghrelin Fights Against Titanium Particle-Induced Inflammatory Osteolysis Through Activation of β-Catenin Signaling Pathway

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Published in 2019 at "Inflammation"

DOI: 10.1007/s10753-019-01026-w

Abstract: Aseptic loosening is a major complication of prosthetic joint surgery, in which exaggerated inflammation and impaired osteoblastogenesis are detected. Ghrelin is a recently discovered neuropeptide that is closely associated with inflammatory conditions and bone regeneration.… read more here.

Keywords: titanium particle; catenin signaling; particle induced; titanium ... See more keywords
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Protein phosphatase 2A as a new target for downregulating osteoclastogenesis and alleviating titanium particle-induced bone resorption.

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Published in 2018 at "Acta biomaterialia"

DOI: 10.1016/j.actbio.2018.04.013

Abstract: Receptor activator of nuclear factor-кB ligand (RANKL)-induced osteoclastogenesis is believed to play a critical role in osteolytic diseases including peri-prosthetic osteolysis (PPO), the primary reason for implant failure and revision surgery. In this study, we… read more here.

Keywords: titanium particle; pp2a; particle induced; resorption ... See more keywords
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Evolution and interaction of corrosive species during the initial NaCl particle induced corrosion on zinc coated skin-passed steel

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Published in 2017 at "Corrosion Science"

DOI: 10.1016/j.corsci.2017.08.001

Abstract: Abstract Within this work, NaCl particle induced corrosion of electrolytically zinc coated, skin-passed steel and especially the influence of the skin-pass texture was investigated. Skin-passing is a wet-rolling procedure that applies a texture on the… read more here.

Keywords: particle induced; zinc coated; corrosion; induced corrosion ... See more keywords
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Emodin attenuates titanium particle‐induced osteolysis and RANKL‐mediated osteoclastogenesis through the suppression of IKK phosphorylation

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Published in 2018 at "Molecular Immunology"

DOI: 10.1016/j.molimm.2018.02.008

Abstract: &NA; Aseptic loosening due to wear particles is a serious challenge for orthopedic surgeons, sabotaging the long‐term success of total joint arthroplasty. The existing treatments for aseptic loosening are still far from satisfactory, necessitating more… read more here.

Keywords: titanium particle; emodin; particle induced; induced osteolysis ... See more keywords
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Bixin protects against particle-induced long-term lung injury in an NRF2-dependent manner.

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Published in 2018 at "Toxicology research"

DOI: 10.1039/c7tx00304h

Abstract: Scope: Particle-induced lung injury is a kind of comprehensive pulmonary disease with not only inflammation but also fibrosis. Bixin is a natural compound that is widely used as a food additive. Our previous studies demonstrated… read more here.

Keywords: induced long; bixin; particle induced; injury ... See more keywords
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Forsythiaside inhibited titanium particle-induced inflammation via the NF-κB signaling pathway and RANKL-induced osteoclastogenesis and titanium particle-induced periprosthetic osteolysis via JNK, p38, and ERK signaling pathways

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Published in 2019 at "RSC Advances"

DOI: 10.1039/c8ra10007a

Abstract: Forsythiaside can act as a candidate drug for the precaution of implant-associated particle-induced osteolysis. read more here.

Keywords: titanium particle; forsythiaside inhibited; particle induced; particle ... See more keywords
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STAT3/IL-6 dependent induction of inflammatory response in osteoblast and osteoclast formation in nanoscale wear particle-induced aseptic prosthesis loosening.

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Published in 2020 at "Biomaterials science"

DOI: 10.1039/d0bm01256d

Abstract: BACKGROUND Aseptic loosening is the main reason for surgical revision after arthroplasty. Although a series of mechanisms have been explored, a specific therapeutic target is still desired. In the present study, we explored the role… read more here.

Keywords: stat3; inflammatory response; formation; particle induced ... See more keywords

The effect of strontium ranelate on titanium particle-induced periprosthetic osteolysis regulated by WNT/β-catenin signaling in vivo and in vitro

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Published in 2021 at "Bioscience Reports"

DOI: 10.1042/bsr20203003

Abstract: Abstract Aseptic loosening following periprosthetic osteolysis is the primary complication that limits the lifetime of total joint arthroplasty (TJA). The wear particles trigger a chronic inflammation response in the periprosthetic tissue and turn over the… read more here.

Keywords: periprosthetic osteolysis; strontium ranelate; ranelate; particle induced ... See more keywords
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Erratum to: Pharmaceutic application of vitamin D3 on particle-induced fibrotic effects through induction of Nrf2 signals.

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Published in 2020 at "Toxicology research"

DOI: 10.1093/toxres/tfaa064

Abstract: [This corrects the article DOI: 10.1093/toxres/tfaa003.]. read more here.

Keywords: vitamin particle; pharmaceutic application; application vitamin; particle induced ... See more keywords
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Cortistatin attenuates titanium particle-induced osteolysis through regulation of TNFR1-ROS-caspase-3 signaling in osteoblasts.

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Published in 2022 at "Annals of the New York Academy of Sciences"

DOI: 10.1111/nyas.14774

Abstract: Aseptic loosening is a major complication of prosthetic joint surgery and is associated with impaired osteoblast homeostasis. Cortistatin (CST) is a neuropeptide that protects against inflammatory conditions. In this study, we found that expression of… read more here.

Keywords: cst; titanium particle; induced osteolysis; particle ... See more keywords