Articles with "particles mice" as a keyword



A shedding analysis after AAV8 CNS injection revealed fragmented viral DNA without evidence of functional AAV particles in mice

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Published in 2024 at "Gene Therapy"

DOI: 10.1038/s41434-024-00447-z

Abstract: Adeno-associated viruses (AAV) are commonly used in the scientific field due to their diverse application range. However, AAV shedding, the release of virions from the host organism, can impact the safety of AAV-based approaches. An… read more here.

Keywords: aav particles; aav; viral dna; particles mice ... See more keywords