Conformational change of the extracellular parts of the CFTR protein during channel gating
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DOI: 10.1007/s00018-018-2777-0
Abstract: Cystic fibrosis can be treated by potentiators, drugs that interact directly with the cystic fibrosis transmembrane conductance regulator (CFTR) Cl− channel to increase its open probability. These substances likely target key conformational changes occurring during… read more here.
Keywords: extracellular parts; cftr protein; parts cftr; conformational changes ... See more keywords