Parvifoline Derivatives as Tubulin Polymerization Inhibitors.
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DOI: 10.1021/acs.jnatprod.8b00860
Abstract: A series of functionalized sesquiterpenoids derived from benzocyclooctene, including natural parvifoline (1), isoparvifoline (3), epoxyparvifoline (5), epoxyisoparvifoline (7), 8,12-oxyparfivoline (9), 8,14-oxyparvifoline (11), and the respective benzoyl derivatives 2, 4, 6, 8, 10, and 12, were… read more here.
Keywords: polymerization; polymerization inhibitors; derivatives tubulin; tubulin polymerization ... See more keywords