The DNMT1-PAS1-PH20 axis drives breast cancer growth and metastasis
Sign Up to like & getrecommendations! Published in 2022 at "Signal Transduction and Targeted Therapy"
DOI: 10.1038/s41392-022-00896-1
Abstract: PH20 is a member of the human hyaluronidase family that degrades hyaluronan in the extracellular matrix and controls tumor progression. Inhibition of DNA methyltransferases (DNMTs) leads to elevated hyaluronan levels; however, whether DNMT inhibitors control… read more here.
Keywords: pas1; breast cancer; growth metastasis; ph20 ... See more keywords
Social dominance hierarchy: toward a genetic and evolutionary understanding
Sign Up to like & getrecommendations! Published in 2020 at "Cell Research"
DOI: 10.1038/s41422-020-0347-0
Abstract: In social animals, the formation of dominance hierarchy is essential for maintaining the stability and efficacy of social groups. A study by Wang and colleagues employ a combination of comparative genomic and functional approaches to… read more here.
Keywords: dominance hierarchy; dominance behavior; dominance; pas1 ... See more keywords