Learnings from past failures: future routes of antimicrobial drug discovery.
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DOI: 10.1016/j.drudis.2021.07.017
Abstract: Despite the unprecedented unmet need to discover new antibiotics, only a few molecules have been registered for clinical use. This shortage is primarily based on the scientific failure in the postgenomic era of drug discovery.… read more here.
Keywords: new antibiotics; drug; drug discovery; past failures ... See more keywords
Learning from past failures: Challenges with monoclonal antibody therapies for COVID-19
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DOI: 10.1016/j.jconrel.2020.11.057
Abstract: COVID-19, the disease caused by infection with SARS-CoV-2, requires urgent development of therapeutic interventions. Due to their safety, specificity, and potential for rapid advancement into the clinic, monoclonal antibodies (mAbs) represent a highly promising class… read more here.
Keywords: challenges monoclonal; antibody therapies; learning past; failures challenges ... See more keywords
Entrepreneurship and information on past failures: A natural experiment
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DOI: 10.1016/j.jfineco.2020.06.021
Abstract: Abstract We analyze how public information on past entrepreneurial failure affects entrepreneurs’ ability to borrow and start new ventures. We exploit a policy shock from 2013 in France, which eliminated a widely used means of… read more here.
Keywords: failures natural; entrepreneurship information; information past; past failures ... See more keywords