Purification of Histidine-Tagged Membrane-Bound Catechol-O-Methyltransferase from Detergent-Solubilized Pichia pastoris Membranes
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DOI: 10.1007/s10337-017-3453-5
Abstract: Catechol-O-methyltransferase (COMT) is an enzyme involved in catecholamine catabolism that is key for the treatment of different neurologic disorders. Actually, there are still unmet needs concerning the development of more selective membrane-bound COMT (hMBCOMT) downstream… read more here.
Keywords: pastoris membranes; membrane bound; catechol methyltransferase; hmbcomt ... See more keywords