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Published in 2017 at "FEBS Letters"
DOI: 10.1002/1873-3468.12567
Abstract: The amino acid transporter PAT1 is typically expressed on the lysosome and plasma membranes in various human tissues. Glycosylation has been shown to be critical for the cell surface expression of PAT1, but not for…
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Keywords:
glycosylation affects;
subcellular distribution;
affects stability;
stability ... See more keywords
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Published in 2019 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2018.09.017
Abstract: The proton-coupled amino acid transporter PAT1 has been postulated to regulate the amino acid-stimulated mTORC1 through two different mechanisms, either it activates mTORC1 by sensing and transducing the lysosomal amino acid signal to mTORC1, or…
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Keywords:
amino acid;
acid transporter;
mtorc1;
pat1 ... See more keywords
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Published in 2020 at "RNA"
DOI: 10.1261/rna.075812.120
Abstract: Pat1 promotes the activation and assembly of multiple proteins during mRNA decay. After deadenylation, the Pat1/Lsm1-7 complex binds to transcripts containing oligo(A) tails, which can be modified by the addition of several terminal uridine residues.…
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Keywords:
decay factors;
lsm1 complex;
lsm1 binding;
lsm1 ... See more keywords