Meta-Path Methods for Prioritizing Candidate Disease miRNAs
Sign Up to like & getrecommendations! Published in 2019 at "IEEE/ACM Transactions on Computational Biology and Bioinformatics"
DOI: 10.1109/tcbb.2017.2776280
Abstract: MicroRNAs (miRNAs) play critical roles in regulating gene expression at post-transcriptional levels. Numerous experimental studies indicate that alterations and dysregulations in miRNAs are associated with important complex diseases, especially cancers. Predicting potential miRNA—disease association is… read more here.
Keywords: mirna disease; disease; meta path; path methods ... See more keywords
Minimum energy path methods and reactivity for enzyme reaction mechanisms: a perspective
Sign Up to like & getrecommendations! Published in 2025 at "Pure and Applied Chemistry"
DOI: 10.1515/pac-2025-0484
Abstract: Abstract In this perspective article, we discuss the link between minimum energy paths and activation parameters for reactions on complex potential energy surfaces involving many possible local minima, as are typically found for enzyme-substrate complexes.… read more here.
Keywords: energy; path methods; energy path; reactivity ... See more keywords