Pathobiologic Mechanisms of Neurodegeneration in Osteopetrosis Derived From Structural and Functional Analysis of 14 ClC‐7 Mutants
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DOI: 10.1002/jbmr.4200
Abstract: ClC‐7 is a chloride‐proton antiporter of the CLC protein family. In complex with its accessory protein Ostm‐1, ClC‐7 localizes to lysosomes and to the osteoclasts' ruffled border, where it plays a critical role in acidifying… read more here.
Keywords: pathobiologic mechanisms; clc; clc mutants; osteopetrosis ... See more keywords