Tumor-associated neutrophils: orchestrating cancer pathobiology and therapeutic resistance
Sign Up to like & getrecommendations! Published in 2021 at "Expert Opinion on Therapeutic Targets"
DOI: 10.1080/14728222.2021.1954162
Abstract: ABSTRACT Introduction: Neutrophils or polymorphonuclear cells (PMNs) account for a considerable portion of the tumor immune stroma. Emerging single-cell transcriptomic analyses have elucidated the striking cellular heterogeneity of PMNs during homeostasis and pathologic conditions and… read more here.
Keywords: pathobiology therapeutic; therapeutic resistance; cancer pathobiology; resistance ... See more keywords
Pathobiology and Therapeutic Implications of Tumor Acidosis.
Sign Up to like & getrecommendations! Published in 2017 at "Current medicinal chemistry"
DOI: 10.2174/0929867323666161228142849
Abstract: Drug resistance and therapeutic failure are important causes of disease relapse and progression and may be considered as major obstacles preventing cure of cancer patients. Tumors use a large number of molecular, biochemical and cellular… read more here.
Keywords: therapeutic implications; pathobiology therapeutic; tumor acidosis; tumor ... See more keywords