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Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-12907-x
Abstract: A common feature shared by systemic fungal pathogens of environmental origin, such as Cryptococcus neoformans, is their ability to adapt to mammalian core body temperature. In C. neoformans, this adaptation is accompanied by Ccr4-mediated decay…
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Keywords:
cryptococcus;
pathogen cryptococcus;
mrna decay;
cryptococcus neoformans ... See more keywords
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Published in 2025 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2521779122
Abstract: The human fungal pathogen Cryptococcus species complex (encompassing Cryptococcus neoformans, Cryptococcus deneoformans, and the Cryptococcus gattii species complexes) exhibits diversity in sexual reproduction, including α-a mating, pseudosexual reproduction, as well as unisexual reproduction initiated from…
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Keywords:
fungal pathogen;
human fungal;
reproduction;
unisexual reproduction ... See more keywords
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Published in 2022 at "eLife"
DOI: 10.1101/2022.08.14.503895
Abstract: The environmental pathogen Cryptococcus neoformans claims over 180,000 lives each year. Survival of this basidiomycete at host CO2 concentrations has only recently been considered an important virulence trait. Through screening gene knockout libraries constructed in…
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Keywords:
co2 tolerance;
thermotolerance;
co2;
pathogen cryptococcus ... See more keywords
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Published in 2025 at "eLife"
DOI: 10.1101/2024.05.20.594937
Abstract: Rtf1 is generally considered to be a subunit of the Paf1 complex (Paf1C), which is a multifunctional protein complex involved in histone modification and RNA biosynthesis at multiple stages. Rtf1 is stably associated with the…
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Keywords:
cryptococcus neoformans;
h2b monoubiquitination;
meningitis causing;
histone ... See more keywords