Articles with "pathogen cryptococcus" as a keyword



Thermotolerance in the pathogen Cryptococcus neoformans is linked to antigen masking via mRNA decay-dependent reprogramming

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Published in 2019 at "Nature Communications"

DOI: 10.1038/s41467-019-12907-x

Abstract: A common feature shared by systemic fungal pathogens of environmental origin, such as Cryptococcus neoformans, is their ability to adapt to mammalian core body temperature. In C. neoformans, this adaptation is accompanied by Ccr4-mediated decay… read more here.

Keywords: cryptococcus; pathogen cryptococcus; mrna decay; cryptococcus neoformans ... See more keywords

Unisexual reproduction in the global human fungal pathogen Cryptococcus neoformans.

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Published in 2025 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2521779122

Abstract: The human fungal pathogen Cryptococcus species complex (encompassing Cryptococcus neoformans, Cryptococcus deneoformans, and the Cryptococcus gattii species complexes) exhibits diversity in sexual reproduction, including α-a mating, pseudosexual reproduction, as well as unisexual reproduction initiated from… read more here.

Keywords: fungal pathogen; human fungal; reproduction; unisexual reproduction ... See more keywords

The RAM signaling pathway links morphology, thermotolerance, and CO2 tolerance in the global fungal pathogen Cryptococcus neoformans

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Published in 2022 at "eLife"

DOI: 10.1101/2022.08.14.503895

Abstract: The environmental pathogen Cryptococcus neoformans claims over 180,000 lives each year. Survival of this basidiomycete at host CO2 concentrations has only recently been considered an important virulence trait. Through screening gene knockout libraries constructed in… read more here.

Keywords: co2 tolerance; thermotolerance; co2; pathogen cryptococcus ... See more keywords

Rtf1 HMD domain facilitates global histone H2B monoubiquitination and regulates morphogenesis and virulence in the meningitis-causing pathogen Cryptococcus neoformans

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Published in 2025 at "eLife"

DOI: 10.1101/2024.05.20.594937

Abstract: Rtf1 is generally considered to be a subunit of the Paf1 complex (Paf1C), which is a multifunctional protein complex involved in histone modification and RNA biosynthesis at multiple stages. Rtf1 is stably associated with the… read more here.

Keywords: cryptococcus neoformans; h2b monoubiquitination; meningitis causing; histone ... See more keywords