Dual Amplification Strategy: Exponential Amplification Reaction and Hybridization Chain Reaction‐Driven Electrochemical Biosensor for Ultrasensitive Pathogen Detection
Sign Up to like & getrecommendations! Published in 2025 at "Electroanalysis"
DOI: 10.1002/elan.70077
Abstract: The growth of nucleic acid‐based diagnostics integrated with electrochemical approaches has fundamentally transformed pathogen detection paradigms, with exponential amplification reaction (EXPAR) and hybridization chain reaction (HCR) emerging as next‐generation alternatives to conventional polymerase chain reaction… read more here.
Keywords: detection; pathogen detection; amplification; chain reaction ... See more keywords
Molecular Enrichment for Qualitative Molecular Pathogen Detection in Food
Sign Up to like & getrecommendations! Published in 2017 at "Food Analytical Methods"
DOI: 10.1007/s12161-017-1103-z
Abstract: Reliable detection of low levels of pathogenic microbial contaminants is one of the most important prerequisites to guarantee safe food production. In this work, the use of molecular enrichment (ME) subsequent to the sample preparation… read more here.
Keywords: detection; molecular enrichment; molecular pathogen; pathogen detection ... See more keywords
Electrochemical biosensors for rapid pathogen detection
Sign Up to like & getrecommendations! Published in 2021 at "Current Opinion in Electrochemistry"
DOI: 10.1016/j.coelec.2021.100750
Abstract: Abstract Rapid pathogen detection is an emerging issue in clinical, environmental and food industry sectors. Biosensors can represent a solution to culture based and molecular methods as they respond to sensitivity, specificity and rapidity needs.… read more here.
Keywords: electrochemical biosensors; pathogen detection; biosensors rapid; rapid pathogen ... See more keywords
Thermodynamic Microenvironment Engineering in Mesoporous Nanoreactors to Enhance Biocatalysis for AI-Empowered Ultrasensitive Pathogen Detection.
Sign Up to like & getrecommendations! Published in 2025 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.5c03889
Abstract: Harmonizing enzyme-support microenvironments to govern thermodynamic interaction landscapes presents a critical yet underexplored frontier in nanobiocatalysis for pathogen detection. Herein, we architecturally engineer mesoporous resorcinol formaldehyde nanospheres (mRFNSs, 9.95 nm pores) with tailored surface chemistry… read more here.
Keywords: chemistry; pathogen detection; thermodynamic microenvironment; microenvironment engineering ... See more keywords
Advances in Molecular Vibrational Spectroscopy for Foodborne Pathogen Detection.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.5c06839
Abstract: Foodborne pathogens threaten global public health and food supply chains, demanding rapid, accurate, and nondestructive detection to prevent outbreaks and economic losses. Conventional methods often require destructive sampling or complex preprocessing, underscoring the critical need… read more here.
Keywords: detection; spectroscopy; pathogen detection; molecular vibrational ... See more keywords
Magnetic-Nanosensor-Based Virus and Pathogen Detection Strategies before and during COVID-19
Sign Up to like & getrecommendations! Published in 2020 at "ACS Applied Nano Materials"
DOI: 10.1021/acsanm.0c02048
Abstract: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), is a threat to the global healthcare system and economic security. As of July 2020, no specific drugs or vaccines… read more here.
Keywords: detection; covid; sars cov; pathogen detection ... See more keywords
A Nanomaterial-Independent Biosensor Based on Gallium Arsenide High-Electron-Mobility Transistors for Rapid and Ultra-Sensitive Pathogen Detection.
Sign Up to like & getrecommendations! Published in 2025 at "ACS sensors"
DOI: 10.1021/acssensors.4c03134
Abstract: Biofield effect transistors (bio-FETs) have emerged as promising candidates for next-generation pathogen detection platforms owing to their exceptional sensitivity and rapid response. However, they generally require complex electrical modulation strategies (e.g., nanomaterial-enhanced channels and external… read more here.
Keywords: detection; electron mobility; biosensor; pathogen detection ... See more keywords
A dataset for developing proteomic tools for pathogen detection via differential cell lysis of whole blood samples
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Data"
DOI: 10.1038/s41597-024-03834-8
Abstract: This data descriptor presents a curated dataset for pathogen detection and identification (Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans) directly from whole-blood samples. The dataset was created using differential cell lysis combined with rapid extraction,… read more here.
Keywords: detection; pathogen detection; whole blood; culture ... See more keywords
MXenes in microbiology and virology: from pathogen detection to antimicrobial applications.
Sign Up to like & getrecommendations! Published in 2025 at "Nanoscale"
DOI: 10.1039/d5nr00477b
Abstract: MXenes, a rapidly emerging class of two-dimensional materials, have demonstrated exceptional versatility and functionality across various domains, including microbiology and virology. Recent advancements in MXene synthesis techniques, encompassing both top-down and bottom-up approaches, have expanded… read more here.
Keywords: pathogen detection; microbiology; virology; microbiology virology ... See more keywords
Amplification-free, OR-gated CRISPR-Cascade reaction for pathogen detection in blood samples
Sign Up to like & getrecommendations! Published in 2025 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2420166122
Abstract: Significance Rapid pathogen detection is crucial for effective disease management, particularly in bloodstream infections. Current molecular diagnostics often require nucleic acid preamplification, adding time and cost. We introduce an amplification-free CRISPR-Cascade assay that detects pathogenic… read more here.
Keywords: detection; crispr cascade; amplification free; pathogen detection ... See more keywords
Rapid Pathogen Detection in Infectious Uveitis Using Nanopore Metagenomic Next-Generation Sequencing: A Preliminary Study.
Sign Up to like & getrecommendations! Published in 2023 at "Ocular immunology and inflammation"
DOI: 10.1080/09273948.2023.2173243
Abstract: PURPOSE We establish an accurate and rapid diagnostic method for pathogen detection in infectious uveitis using nanopore metagenomic next-generation sequencing (NGS). METHODS In eight patients with suspected infectious uveitis, we prospectively compared the accuracy and… read more here.
Keywords: nanopore metagenomic; pathogen detection; using nanopore; infectious uveitis ... See more keywords