Characterization of a pathogen reduced human platelet lysate
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DOI: 10.1016/j.jcyt.2018.02.168
Abstract: As more manufactured cellular therapies move into clinical use, there is an increasing call for cell culture media supplements that are of high quality, compatible with different cell types, and not supply-limited. Human platelet lysate… read more here.
Keywords: pathogen reduced; characterization pathogen; human platelet; platelet lysate ... See more keywords
The impact of pathogen‐reduced platelets in acute leukaemia treatment on the total blood product requirement: a subgroup analysis of an EFFIPAP randomised trial
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DOI: 10.1111/tme.12848
Abstract: To evaluate the impact of pathogen‐reduced (PR) platelet transfusions on blood products requirement for clinical practice. read more here.
Keywords: blood; reduced platelets; impact pathogen; pathogen reduced ... See more keywords
Quarantine versus pathogen‐reduced plasma‐coagulation factor content and rotational thromboelastometry coagulation
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DOI: 10.1111/trf.13935
Abstract: Different types of fresh‐frozen plasma (FFP) exist, and the concentrations of plasma proteins vary between individuals and blood groups. Furthermore, processing may also influence the content. Quarantine‐stored plasma (qFFP) and plasma that was pathogen‐reduced using… read more here.
Keywords: versus pathogen; coagulation; quarantine versus; pathogen reduced ... See more keywords
Phased implementation of pathogen‐reduced platelets in a health system facilitates increased manufacturing at the blood center
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DOI: 10.1111/trf.15480
Abstract: Pathogen reduction treatment (PRT) reduces the risk of transfusion‐transmitted infections from established and emerging organisms. Manufacturing, however, is complex. In our university health system, we phased in pathogen‐reduced platelets (PR PLTs) by patient population. We… read more here.
Keywords: health system; pathogen; reduced platelets; pathogen reduced ... See more keywords
Longitudinal analysis of annual national hemovigilance data to assess pathogen reduced platelet transfusion trends during conversion to routine universal clinical use and 7‐day storage
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DOI: 10.1111/trf.17285
Abstract: France converted to universal pathogen reduced (PR; amotosalen/UVA) platelets in 2017 and extended platelet component (PC) shelf‐life from 5‐ to 7‐days in 2018 and 2019. Annual national hemovigilance (HV) reports characterized longitudinal PC utilization and… read more here.
Keywords: transfusion; national hemovigilance; annual national; pathogen reduced ... See more keywords
Efficacy and Safety of Pathogen-Reduced Platelets Compared with Standard Apheresis Platelets: A Systematic Review of RCTs
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DOI: 10.3390/pathogens11060639
Abstract: In this systematic review, we evaluate the efficacy and safety of blood components treated with pathogen reduction technologies (PRTs). We searched the Medline, Embase, Scopus, Ovid, and Cochrane Library to identify RCTs evaluating PRTs. Risk… read more here.
Keywords: pathogen reduced; review rcts; compared standard; plt recipients ... See more keywords