Economic Analyses of Pathogen-Reduction Technologies in Blood Transfusion: A Systematic Literature Review
Sign Up to like & getrecommendations! Published in 2021 at "Applied Health Economics and Health Policy"
DOI: 10.1007/s40258-020-00612-6
Abstract: Technologies used in the processing of whole blood and blood component products, including pathogen reduction, are continuously being adopted into blood transfusion workflows to improve process efficiencies. However, the economic implications of these technologies are… read more here.
Keywords: blood; pathogen reduction; blood transfusion; systematic literature ... See more keywords
Impact of pathogen-reduction technologies on COVID-19 convalescent plasma potency
Sign Up to like & getrecommendations! Published in 2021 at "Transfusion Clinique et Biologique"
DOI: 10.1016/j.tracli.2021.02.005
Abstract: Pathogen reduction technologies (PRT) have been recommended by many regulatory authorities to minimize the residual risk of transfusion-transmitted infections associated with COVID19 convalescent plasma. While its impact on safety and its cost-effectiveness are nowadays well… read more here.
Keywords: reduction technologies; convalescent plasma; pathogen reduction; convalescent ... See more keywords
Our experience in riboflavin and ultraviolet light pathogen reduction technology for platelets: from platelet production to patient care
Sign Up to like & getrecommendations! Published in 2018 at "Transfusion"
DOI: 10.1111/trf.14797
Abstract: Pathogen reduction technology (PRT) enhances blood component safety, but its implementation is hampered by loss of blood quality and cost. read more here.
Keywords: experience riboflavin; pathogen reduction; reduction technology;
Effect of leukoreduction and pathogen reduction on the hemostatic function of whole blood
Sign Up to like & getrecommendations! Published in 2019 at "Transfusion"
DOI: 10.1111/trf.15175
Abstract: There is renewed interest in the use of whole blood (WB) for resuscitation of patients in hemorrhagic shock. Leukoreduction with platelet‐sparing filters and pathogen reduction may be used to improve the safety profile of WB,… read more here.
Keywords: leukoreduction; leukoreduction pathogen; reduction hemostatic; pathogen reduction ... See more keywords
Proceedings of the Food and Drug Administration public workshop on pathogen reduction technologies for blood safety 2018 (Commentary, p. 3026)
Sign Up to like & getrecommendations! Published in 2019 at "Transfusion"
DOI: 10.1111/trf.15344
Abstract: On November 29, 2018, experts in the field of infectious diseases, pathogen reduction technologies (PRTs) and other participants from blood centers, academia, and industry gathered at the Food and Drug Administration (FDA) White Oak Campus… read more here.
Keywords: reduction technologies; blood safety; safety; blood ... See more keywords
Inactivation of Plasmodium falciparum in whole blood using the amustaline and glutathione pathogen reduction technology
Sign Up to like & getrecommendations! Published in 2020 at "Transfusion"
DOI: 10.1111/trf.15734
Abstract: Risk of transfusion‐transmitted (TT) malaria is mainly associated with whole blood (WB) or red blood cell (RBC) transfusion. Risk mitigation relies mostly on donor deferral while a limited number of countries perform blood testing, both… read more here.
Keywords: using amustaline; plasmodium falciparum; blood; pathogen reduction ... See more keywords
Sepsis from an apheresis platelet contaminated with Acinetobacter calcoaceticus/baumannii complex bacteria and Staphylococcus saprophyticus after pathogen reduction
Sign Up to like & getrecommendations! Published in 2020 at "Transfusion"
DOI: 10.1111/trf.15951
Abstract: Strategies to reduce platelet (PLT) bacterial contamination include donor screening, skin disinfection, sample diversion, bacterial culture, pathogen reduction (PR), and day‐of‐transfusion tests. We report bacterial sepsis following a pathogen‐reduced PLT transfusion. read more here.
Keywords: pathogen reduction; pathogen; platelet; sepsis apheresis ... See more keywords
Robust inactivation of Plasmodium falciparum in red blood cell concentrates using amustaline and glutathione pathogen reduction
Sign Up to like & getrecommendations! Published in 2022 at "Transfusion"
DOI: 10.1111/trf.16867
Abstract: Plasmodium falciparum is the parasite responsible for most malaria cases globally. The risk of transfusion‐transmitted malaria (TTM) is mitigated by donor deferrals and blood screening strategies, which adversely impact blood availability. Previous studies showed robust… read more here.
Keywords: plasmodium falciparum; robust inactivation; amustaline glutathione; pathogen reduction ... See more keywords
Cost‐effectiveness of pathogen reduction technology for plasma and platelets in Québec: A focus on potential emerging pathogens
Sign Up to like & getrecommendations! Published in 2022 at "Transfusion"
DOI: 10.1111/trf.16926
Abstract: The last economic evaluation of pathogen reduction technology (PRT) in Canada was conducted in 2007. We reassessed the cost‐effectiveness of PRT in the province of Québec (which has its own blood supplier) and included an… read more here.
Keywords: reduction technology; cost; pathogen reduction; emerging pathogens ... See more keywords
Mitigating the risk of transfusion‐transmitted infections with vector‐borne agents solely by means of pathogen reduction
Sign Up to like & getrecommendations! Published in 2022 at "Transfusion"
DOI: 10.1111/trf.16950
Abstract: This study evaluated whether pathogen reduction technology (PRT) in plasma and platelets using amotosalen/ultraviolet A light (A/UVA) or in red blood cells using amustaline/glutathione (S‐303/GSH) may be used as the sole mitigation strategy preventing transfusion‐transmitted… read more here.
Keywords: transfusion transmitted; risk transfusion; pathogen reduction; mitigating risk ... See more keywords
Effects of pre‐freeze pathogen reduction with riboflavin and UV light on red cells stored post‐thaw in AS‐3 additive solution
Sign Up to like & getrecommendations! Published in 2023 at "Transfusion"
DOI: 10.1111/trf.17313
Abstract: Pathogen reduction technology (PRT) may improve the safety of RBCs for transfusion. As the Czech Republic considers PRT, we asked what effects riboflavin and UV light PRT pre‐freezing has on the post‐thaw recovery and properties… read more here.
Keywords: riboflavin light; pathogen reduction; post thaw;