Pathogen richness and abundance predict patterns of adaptive major histocompatibility complex variation in insular amphibians
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Ecology"
DOI: 10.1111/mec.14242
Abstract: The identification of the factors responsible for genetic variation and differentiation at adaptive loci can provide important insights into the evolutionary process and is crucial for the effective management of threatened species. We studied the… read more here.
Keywords: pathogen richness; abundance predict; predict patterns; variation ... See more keywords
Evolution of major histocompatibility complex gene copy number
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1007015
Abstract: MHC genes, which code for proteins responsible for presenting pathogen-derived antigens to the host immune system, show remarkable copy-number variation both between and within species. However, the evolutionary forces driving this variation are poorly understood.… read more here.
Keywords: pathogen richness; copy number; pathogen; number ... See more keywords