The Histone Modification Code in the Pathogenesis of Autoimmune Diseases
Sign Up to like & getrecommendations! Published in 2017 at "Mediators of Inflammation"
DOI: 10.1155/2017/2608605
Abstract: Autoimmune diseases are chronic inflammatory disorders caused by a loss of self-tolerance, which is characterized by the appearance of autoantibodies and/or autoreactive lymphocytes and the impaired suppressive function of regulatory T cells. The pathogenesis of… read more here.
Keywords: histone modifications; autoimmune; diseases histone; autoimmune diseases ... See more keywords
Pathogenesis of Autoimmune Cytopenias in Inborn Errors of Immunity Revealing Novel Therapeutic Targets
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.846660
Abstract: Autoimmune diseases are usually associated with environmental triggers and genetic predisposition. However, a few number of autoimmune diseases has a monogenic cause, mostly in children. These diseases may be the expression, isolated or associated with… read more here.
Keywords: inborn errors; autoimmune; errors immunity; pathogenesis autoimmune ... See more keywords
The role of YKL-40 in the pathogenesis of autoimmune diseases: a comprehensive review
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.67587
Abstract: YKL-40, a chitinase-3-like protein 1 (CHI3L1) or human cartilage glycoprotein 39 (HC gp-39), is expressed and secreted by various cell-types including macrophages, chondrocytes, fibroblast-like synovial cells and vascular smooth muscle cells. Its biological function is… read more here.
Keywords: disease; autoimmune diseases; role ykl; ykl pathogenesis ... See more keywords