Regulation of Matrix Metalloproteinase in the Pathogenesis of Diabetic Retinopathy.
Sign Up to like & getrecommendations! Published in 2017 at "Progress in molecular biology and translational science"
DOI: 10.1016/bs.pmbts.2017.02.004
Abstract: Diabetic retinopathy, a progressive disease, is the major cause of acquired blindness in the developed countries. Despite cutting-edge research in the field, the exact mechanism of this multifactorial disease remains elusive. Matrix metalloproteinases (MMPs) degrade… read more here.
Keywords: retinopathy; diabetic retinopathy; pathogenesis diabetic; matrix ... See more keywords
Dynamic Phenotypes and Molecular Mechanisms to Understand the Pathogenesis of Diabetic Nephropathy in Two Widely Used Animal Models of Type 2 Diabetes Mellitus
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.00172
Abstract: Objective We aimed to characterize the pathogenesis of diabetic nephropathy (DN) in two commonly used type 2 diabetes mellitus (T2DM) animal models and explore the preliminary molecular mechanisms underlying DN in two models. Methods To… read more here.
Keywords: nephropathy two; pathogenesis diabetic; pathology; type diabetes ... See more keywords
The role of aldosterone in the pathogenesis of diabetic retinopathy
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1163787
Abstract: Aldosterone, as a mineralocorticoid of adrenal origin, has effects that are not limited to the urinary tract. As an important regulator in Vasoactive hormone pathways, aldosterone may play an effect in the pathogenesis of diabetic… read more here.
Keywords: aldosterone; pathogenesis diabetic; aldosterone pathogenesis; role aldosterone ... See more keywords
The RAGE/DIAPH1 Signaling Axis & Implications for the Pathogenesis of Diabetic Complications
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23094579
Abstract: Increasing evidence links the RAGE (receptor for advanced glycation end products)/DIAPH1 (Diaphanous 1) signaling axis to the pathogenesis of diabetic complications. RAGE is a multi-ligand receptor and through these ligand–receptor interactions, extensive maladaptive effects are… read more here.
Keywords: diaph1 signaling; pathogenesis diabetic; diabetic complications; complications rage ... See more keywords
The Role of MicroRNA in the Pathogenesis of Diabetic Nephropathy
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DOI: 10.3390/ijms24076214
Abstract: Diabetic nephropathy is one of the most common and severe complications of diabetes mellitus, affecting one in every five patients suffering from diabetes. Despite extensive research, the exact pathogenesis of diabetic nephropathy is still unclear.… read more here.
Keywords: microrna pathogenesis; role microrna; diabetic nephropathy; pathogenesis diabetic ... See more keywords