MicroRNAs in hypertrophic cardiomyopathy: pathogenesis, diagnosis, treatment potential and roles as clinical biomarkers
Sign Up to like & getrecommendations! Published in 2022 at "Heart Failure Reviews"
DOI: 10.1007/s10741-022-10231-z
Abstract: Hypertrophic cardiomyopathy (HCM) is the most common heritable cardiomyopathy and is characterized by increased left ventricular wall thickness, but existing diagnostic and treatment approaches face limitations. MicroRNAs (miRNAs) are type of noncoding RNA molecule that… read more here.
Keywords: hypertrophic cardiomyopathy; cardiomyopathy pathogenesis; treatment; pathogenesis diagnosis ... See more keywords
Merkel Cell Carcinoma: Updates on Pathogenesis, Diagnosis, and Management
Sign Up to like & getrecommendations! Published in 2018 at "Current Dermatology Reports"
DOI: 10.1007/s13671-018-0221-1
Abstract: Purpose of ReviewTo describe updates on the pathogenesis, diagnosis, and management of Merkel cell carcinoma (MCC).Recent FindingsSequencing studies revealed that MCCs have either a low mutational burden and integrated Merkel cell polyomavirus (MCPyV), or they… read more here.
Keywords: diagnosis management; pathogenesis diagnosis; merkel cell;
The pathogenesis, diagnosis and clinical manifestations of steroid-induced osteonecrosis.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of autoimmunity"
DOI: 10.1016/j.jaut.2020.102460
Abstract: Corticosteroid associated osteonecrosis is bone death resulting from the use of chronic glucocorticoids and most commonly affects the femoral head, although the bones such as around knee joint, wrist joint and ankle joint can be… read more here.
Keywords: osteonecrosis; associated osteonecrosis; pathogenesis; pathogenesis diagnosis ... See more keywords
Alopecia areata: What's new in epidemiology, pathogenesis, diagnosis, and therapeutic options?
Sign Up to like & getrecommendations! Published in 2017 at "Journal of dermatological science"
DOI: 10.1016/j.jdermsci.2016.10.004
Abstract: Alopecia areata (AA) is a common and stressful disorder that results in hair loss, and resistant to treatment in some cases. Experimental and clinical evidence suggests that AA is caused by autoimmune attack against the… read more here.
Keywords: alopecia areata; epidemiology pathogenesis; areata new; epidemiology ... See more keywords
Pathogenesis, diagnosis and therapeutic strategies in WHIM syndrome immunodeficiency
Sign Up to like & getrecommendations! Published in 2017 at "Expert Opinion on Orphan Drugs"
DOI: 10.1080/21678707.2017.1375403
Abstract: ABSTRACT Introduction: WHIM syndrome is a rare combined primary immunodeficiency disorder caused by autosomal dominant gain-of-function mutations in the chemokine receptor CXCR4. It is the only Mendelian condition known to be caused by mutation of… read more here.
Keywords: immunodeficiency; whim syndrome; genetics; pathogenesis diagnosis ... See more keywords
Postoperative diarrhea in Crohn’s disease: Pathogenesis, diagnosis, and therapy
Sign Up to like & getrecommendations! Published in 2023 at "World Journal of Clinical Cases"
DOI: 10.12998/wjcc.v11.i1.7
Abstract: Diarrhea is a frequent symptom in postoperative patients with Crohn’s diseases (CD), and several different mechanisms likely account for postoperative diarrhea in CD. A targeted strategy based on a comprehensive understanding of postoperative diarrhea is… read more here.
Keywords: disease pathogenesis; crohn disease; diarrhea; postoperative diarrhea ... See more keywords
Etiology, pathogenesis, and diagnosis of neovascular glaucoma.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of ophthalmology"
DOI: 10.18240/ijo.2022.06.20
Abstract: Neovascular glaucoma is defined as iris and/or anterior chamber angle neovascularization associated with increased intraocular pressure. It is a secondary glaucoma that is most frequently caused by severe retinal ischemia. The most common diseases responsible… read more here.
Keywords: glaucoma; neovascular glaucoma; etiology; pathogenesis diagnosis ... See more keywords
Hidradenitis suppurativa: from pathogenesis to diagnosis and treatment
Sign Up to like & getrecommendations! Published in 2017 at "Clinical, Cosmetic and Investigational Dermatology"
DOI: 10.2147/ccid.s111019
Abstract: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease primarily affecting apocrine gland-rich areas of the body and presenting with painful nodules, abscesses, sinus tracts, and scarring. HS is a multifactorial disease in which genetic… read more here.
Keywords: diagnosis treatment; suppurativa pathogenesis; hidradenitis suppurativa; pathogenesis diagnosis ... See more keywords
Research progress of exosomes in pathogenesis, diagnosis, and treatment of ocular diseases
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2023.1100310
Abstract: Exosomes are natural extracellular vesicles with a diameter of 30–150 nm, which exist in biological fluids and contain biomolecules related to the parent cell, such as proteins, nucleic acids, lipids, etc. It has a wide… read more here.
Keywords: diagnosis; progress exosomes; pathogenesis diagnosis; ocular diseases ... See more keywords
Exosomes in osteoarthritis: Updated insights on pathogenesis, diagnosis, and treatment
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.949690
Abstract: Osteoarthritis (OA) has remained a prevalent public health problem worldwide over the past decades. OA is a global challenge because its specific pathogenesis is unclear, and no effective disease-modifying drugs are currently available. Exosomes are… read more here.
Keywords: osteoarthritis updated; exosomes osteoarthritis; updated insights; insights pathogenesis ... See more keywords
Cerebral malaria induced by plasmodium falciparum: clinical features, pathogenesis, diagnosis, and treatment
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.939532
Abstract: Cerebral malaria (CM) caused by Plasmodium falciparum is a fatal neurological complication of malaria, resulting in coma and death, and even survivors may suffer long-term neurological sequelae. In sub-Saharan Africa, CM occurs mainly in children… read more here.
Keywords: plasmodium falciparum; treatment; pathogenesis diagnosis; cerebral malaria ... See more keywords