Transcriptional profile of human macrophages stimulated by ultra-high molecular weight polyethylene particulate debris of orthopedic implants uncovers a common gene expression signature of rheumatoid arthritis.
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DOI: 10.1016/j.actbio.2017.11.001
Abstract: Osteolysis is a serious postoperative complication of total joint arthroplasty that leads to aseptic loosening and surgical revision. Osteolysis is a chronic destructive process that occurs when host macrophages recognize implant particles and release inflammatory… read more here.
Keywords: pathogenesis osteolysis; gene expression; ultra high; osteolysis ... See more keywords