Thrombospondin-2 is up-regulated by TGFβ2 and increases fibronectin expression in human trabecular meshwork cells.
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DOI: 10.1016/j.exer.2019.107820
Abstract: Elevated intraocular pressure (IOP) is a major risk factor for the development of primary open-angle glaucoma (POAG). This is from an increased aqueous humor (AH) outflow resistance through the trabecular meshwork (TM). The pathogenic mechanisms… read more here.
Keywords: trabecular meshwork; fibronectin; pathogenesis poag; ecm ... See more keywords