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Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27036
Abstract: HOX genes are involved with normal development, cell identity, cell differentiation, cell metabolism, apoptosis, autophagy as well as with diseases such as tumor pathogenesis and progression. In particular, the genes belonging to HOX paralogous 13…
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Keywords:
tumor pathogenesis;
progression;
hox;
pathogenesis progression ... See more keywords
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Published in 2024 at "Physiological reviews"
DOI: 10.1152/physrev.00030.2022
Abstract: Alzheimer disease (AD) is associated with multiple etiologies and pathological mechanisms, among which oxidative stress (OS) appears as a major determinant. Intriguingly, OS arises in various pathways regulating brain functions, and it seems to link…
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Keywords:
alzheimer disease;
brain;
oxidative damage;
pathogenesis progression ... See more keywords
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Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/1315248
Abstract: Alzheimer's disease (AD) and Parkinson's disease (PD) are the most common neurodegenerative disorders of the central nervous system (CNS). Increasing evidence supports the view that dysfunction of innate immune cells initiated by accumulated and misfolded…
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Keywords:
pathogenesis progression;
innate adaptive;
immune cells;
adaptive immune ... See more keywords
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Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.980231
Abstract: Coronavirus disease 2019 (COVID-19), an infectious acute respiratory disease caused by a newly emerging RNA virus, is a still-growing pandemic that has caused more than 6 million deaths globally and has seriously threatened the lives…
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Keywords:
emerging regulators;
rnas emerging;
pathogenesis progression;
circular rnas ... See more keywords
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Published in 2021 at "Biology"
DOI: 10.3390/biology10090918
Abstract: Simple Summary Treatment regimens for patients with advanced disease are limited and the mortality rate is high in these patients. A better understanding on pathogenesis and progression of cancer is critical for the development of…
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Keywords:
coding rnas;
non coding;
crc;
cancer ... See more keywords
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Published in 2025 at "Biomolecules"
DOI: 10.3390/biom15010120
Abstract: Acral melanoma is a distinct subtype of cutaneous malignant melanoma that uniquely occurs on ultraviolet (UV)-shielded, glabrous skin of the palms, soles, and nail beds. While acral melanoma only accounts for 2–3% of all melanomas,…
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Keywords:
acral melanoma;
pathogenesis progression;
melanoma review;
melanoma ... See more keywords
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Published in 2022 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.343900
Abstract: Nrg-1β1 dysregulation regulates responses in EAE. The current data propose that Nrg-1β1 can modulate both the innate and adaptive immune responses at the CNS levels, and its effects peripherally are mainly through the regulation of…
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Keywords:
pathogenesis progression;
neuregulin 1beta1;
emerging role;
role neuregulin ... See more keywords
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Published in 2019 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.31972
Abstract: The really interesting new gene (RING) finger protein 8 (RNF8) is a central factor in DNA double strand break (DSB) signal transduction. DSB damage is the most toxic type of DNA damage to cells and…
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Keywords:
dna damage;
damage;
cancer;
factor ... See more keywords