New Mutations and Pathogenesis of Pulmonary Hypertension: Progress and Puzzles in Disease Pathogenesis
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DOI: 10.1161/circresaha.122.320084
Abstract: Pulmonary arterial hypertension (PAH) is a complex multifactorial disease with poor prognosis characterized by functional and structural alterations of the pulmonary circulation causing marked increase in pulmonary vascular resistance, ultimately leading to right heart failure… read more here.
Keywords: pathogenesis pulmonary; pulmonary hypertension; hypertension; mutations pathogenesis ... See more keywords
Insights into the Pathogenesis of Pulmonary Fibrosis from Genetic Diseases.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of respiratory cell and molecular biology"
DOI: 10.1165/rcmb.2021-0557tr
Abstract: Pulmonary fibrosis is a disease process associated with significant morbidity and mortality, with limited therapeutic options due to an incomplete understanding of the underlying pathophysiology. Mechanisms driving the fibrotic cascade have been elucidated through studies… read more here.
Keywords: pathogenesis pulmonary; genetic diseases; fibrosis genetic; pulmonary fibrosis ... See more keywords