The role of NFAT in the pathogenesis and targeted therapy of hematological malignancies.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2022.174889
Abstract: The nuclear factor of activated T cells (NFAT) family is well known for the survival of hemopoietic cells and plays an important role in the immune response. In recent decades, NFAT alteration was discovered in… read more here.
Keywords: role nfat; nfat pathogenesis; pathogenesis targeted; targeted therapy ... See more keywords
Role of Interleukin- (IL-) 17 in the Pathogenesis and Targeted Therapies in Spondyloarthropathies
Sign Up to like & getrecommendations! Published in 2018 at "Mediators of Inflammation"
DOI: 10.1155/2018/2403935
Abstract: Spondyloarthropathy (SpA) is a unique type of joint inflammation characterized by coexisting erosive bone damage and pathological new bone formation. Previous genetic association studies have demonstrated that several cytokine pathways play a critical role in… read more here.
Keywords: interleukin pathogenesis; pathogenesis targeted; spa; pathogenesis ... See more keywords
Platelets in Hepatocellular Carcinoma—From Pathogenesis to Targeted Therapy
Sign Up to like & getrecommendations! Published in 2025 at "Cancers"
DOI: 10.3390/cancers17142391
Abstract: Simple Summary Platelets are increasingly recognized as key contributors to the development and progression of hepatocellular carcinoma (HCC), the most common type of liver cancer. Traditionally known for their role in blood clotting, platelets are… read more here.
Keywords: carcinoma; pathogenesis targeted; hepatocellular carcinoma; targeted therapy ... See more keywords
IgA Nephropathy: Current Understanding and Perspectives on Pathogenesis and Targeted Treatment
Sign Up to like & getrecommendations! Published in 2023 at "Diagnostics"
DOI: 10.3390/diagnostics13020303
Abstract: Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis worldwide, with varied clinical and histopathological features between individuals, particularly across races. As an autoimmune disease, IgAN arises from consequences of increased circulating levels of… read more here.
Keywords: perspectives pathogenesis; iga nephropathy; current understanding; nephropathy current ... See more keywords