Genetics, pathogenesis and therapeutic developments for Usher syndrome type 2.
Sign Up to like & getrecommendations! Published in 2021 at "Human genetics"
DOI: 10.1007/s00439-021-02324-w
Abstract: Usher syndrome (USH) is a rare, autosomal recessively inherited disorder resulting in a combination of sensorineural hearing loss and a progressive loss of vision resulting from retinitis pigmentosa (RP), occasionally accompanied by an altered vestibular… read more here.
Keywords: genetics; syndrome type; therapeutic developments; usher syndrome ... See more keywords
Th9 cells and IL-9 in autoimmune disorders: Pathogenesis and therapeutic potentials.
Sign Up to like & getrecommendations! Published in 2017 at "Human immunology"
DOI: 10.1016/j.humimm.2016.12.010
Abstract: Naïve CD4+ T cells are pleiotropically divided into various T helper (Th) cell subsets, according to their pivotal roles in the regulation of immune responses. The differentiation of Th9 cells, an interleukin (IL)-9 producing subset,… read more here.
Keywords: disorders pathogenesis; th9 cells; autoimmune disorders; therapeutic potentials ... See more keywords
Recent advances in understanding pathogenesis and therapeutic strategies of Systemic Lupus Erythematosus.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.107028
Abstract: Systemic lupus erythematosus (SLE) is a multi-system-involving autoimmune disorder mainly affecting young and middle-aged women. Autoantibodies formation and immune complex deposition as well as other immune mechanisms contribute to heterogeneous clinical presentation, which leads to… read more here.
Keywords: systemic lupus; understanding pathogenesis; lupus erythematosus; therapeutic strategies ... See more keywords
miRNA in Hepatocellular Carcinoma: Pathogenesis and Therapeutic Approaches.
Sign Up to like & getrecommendations! Published in 2017 at "Critical reviews in eukaryotic gene expression"
DOI: 10.1615/critreveukaryotgeneexpr.2017019539
Abstract: Hepatocellular carcinoma (HCC) is a worldwide disease. Because therapeutic measures are ineffective, HCC currently has a poor prognosis. The main causes of HCCs are alcoholism, hepatitis, and metabolic syndrome. Normally hygieinic studies revealed that there… read more here.
Keywords: hepatocellular carcinoma; carcinoma pathogenesis; mirna hepatocellular; carcinoma ... See more keywords
Mitochondrial Dynamics: Pathogenesis and Therapeutic Targets of Vascular Diseases
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2021.770574
Abstract: Vascular diseases, particularly atherosclerosis, are associated with high morbidity and mortality. Endothelial cell (EC) or vascular smooth muscle cell (VSMC) dysfunction leads to blood vessel abnormalities, which cause a series of vascular diseases. The mitochondria… read more here.
Keywords: dynamics pathogenesis; therapeutic targets; pathogenesis therapeutic; vascular diseases ... See more keywords
Crescentic Glomerulonephritis: Pathogenesis and Therapeutic Potential of Human Amniotic Stem Cells
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2021.724186
Abstract: Chronic kidney disease (CKD) leads to significant morbidity and mortality worldwide. Glomerulonephritis (GN) is the second leading cause of CKD resulting in end stage renal failure. The most severe and rapidly progressive type of GN… read more here.
Keywords: glomerulonephritis pathogenesis; crescentic glomerulonephritis; human amniotic; pathogenesis therapeutic ... See more keywords
Hepatocellular Carcinoma: Molecular Pathogenesis and Therapeutic Advances
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14030621
Abstract: Simple Summary Patients with unresectable hepatocellular carcinoma (HCC), the most common primary tumor of the liver, have poor prognosis and are increasing worldwide. The recent approval of several novel therapies for HCC was long expected,… read more here.
Keywords: hepatocellular carcinoma; carcinoma molecular; liver; hcc ... See more keywords
Vitiligo, from Pathogenesis to Therapeutic Advances: State of the Art
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24054910
Abstract: Vitiligo is an acquired hypopigmentation of the skin due to a progressive selective loss of melanocytes; it has a prevalence of 1–2% and appears as rounded, well-demarcated white macules. The etiopathology of the disease has… read more here.
Keywords: advances state; therapeutic advances; pathogenesis; vitiligo pathogenesis ... See more keywords
Enterococci—Involvement in Pathogenesis and Therapeutic Potential in Cancer Treatment: A Mini-Review
Sign Up to like & getrecommendations! Published in 2022 at "Pathogens"
DOI: 10.3390/pathogens11060687
Abstract: Enterococcus spp. are Gram-positive, heterogeneous lactic acid bacteria inhabiting various environments. Several species of Enterococci are considered to be able to stimulate the immune system and play an important role in intestinal homeostasis. Some Enterococci… read more here.
Keywords: enterococci involvement; involvement pathogenesis; pathogenesis therapeutic; cancer treatment ... See more keywords