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Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.979307
Abstract: Triptolide (TP) is the major pharmacologically active ingredient and toxic component of Tripterygium wilfordii Hook. f. However, its clinical potential is limited by a narrow therapeutic window and multiple organ toxicity, especially hepatotoxicity. Furthermore, TP-induced…
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Keywords:
molecular pathogenesis;
hepatotoxicity;
pathogenesis triptolide;
triptolide induced ... See more keywords