Coexisting Retrocerebellar Arachnoid Cyst and Chiari Type 1 Malformation: 3 Pediatric Cases of Surgical Management Tailored To The Pathogenic Mechanism and Systematic Review Of The Literature.
Sign Up to like & getrecommendations! Published in 2020 at "World neurosurgery"
DOI: 10.1016/j.wneu.2020.12.094
Abstract: INTRODUCTION Arachnoid cysts are benign cerebrospinal fluid collection within a duplication of arachnoid membrane and, when found in the retrocerebellar site, they may be associated with tonsils herniation. This rare situation of coexisting retrocerebellar arachnoid… read more here.
Keywords: surgical management; coexisting retrocerebellar; cyst; pathogenic mechanism ... See more keywords
Inflammasome as a Key Pathogenic Mechanism in Endometriosis.
Sign Up to like & getrecommendations! Published in 2017 at "Current drug targets"
DOI: 10.2174/1389450117666160709013850
Abstract: BACKGROUND Endometriosis remains a challenging condition for clinicians to treat. To improve our results, we have to develop new treatment strategies based on pathophysiological mechanisms targeting the etiologic and pathogenic processes involved. OBJECTIVES Revise new… read more here.
Keywords: endometriosis; inflammasome key; mechanism endometriosis; key pathogenic ... See more keywords
Investigation of Pathogenic Mechanism of Covert Mortality Nodavirus Infection in Penaeus vannamei
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.904358
Abstract: Viral covert mortality disease (VCMD), also known as running mortality syndrome (RMS), is caused by covert mortality nodavirus (CMNV) and has impacted the shrimp farming industry in Asia and Latin America in recent years. The… read more here.
Keywords: covert mortality; penaeus vannamei; infection; mortality nodavirus ... See more keywords
Integrated Analysis of Expression Profile and Potential Pathogenic Mechanism of Temporal Lobe Epilepsy With Hippocampal Sclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2022.892022
Abstract: Objective To investigate the potential pathogenic mechanism of temporal lobe epilepsy with hippocampal sclerosis (TLE+HS) by analyzing the expression profiles of microRNA/ mRNA/ lncRNA/ DNA methylation in brain tissues. Methods Brain tissues of six patients… read more here.
Keywords: lobe epilepsy; expression; temporal lobe; mechanism temporal ... See more keywords
Systems Approach to Pathogenic Mechanism of Type 2 Diabetes and Drug Discovery Design Based on Deep Learning and Drug Design Specifications
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22010166
Abstract: In this study, we proposed a systems biology approach to investigate the pathogenic mechanism for identifying significant biomarkers as drug targets and a systematic drug discovery strategy to design a potential multiple-molecule targeting drug for… read more here.
Keywords: design specifications; drug; type diabetes; drug discovery ... See more keywords