Multidisciplinary team directed analysis of whole genome sequencing reveals pathogenic non-coding variants in molecularly undiagnosed inherited retinal dystrophies
Sign Up to like & getrecommendations! Published in 2022 at "Human Molecular Genetics"
DOI: 10.1093/hmg/ddac227
Abstract: Abstract The purpose of this paper is to identify likely pathogenic non-coding variants in inherited retinal dystrophy (IRD) genes, using genome sequencing (GS). Patients with IRD were recruited to the study and underwent comprehensive ophthalmological… read more here.
Keywords: non; coding variants; inherited retinal; pathogenic non ... See more keywords
Can abundance of sensory proteins distinguish between pathogenic and non-pathogenic bacteria?
Sign Up to like & getrecommendations! Published in 2020 at "Applied and environmental microbiology"
DOI: 10.1128/aem.00478-20
Abstract: Signal Transduction Systems are essential for microorganisms to respond to their ever changing environment. It can be distinguished into one-component systems, two-component system, and extracytoplasmic-function σ factors. Abundances of a few signal-transducing proteins, termed herein… read more here.
Keywords: abundance; non pathogenic; sps; sensory proteins ... See more keywords
Metabolomics Study on Pathogenic and Non-pathogenic E. coli with Closely Related Genomes with a Focus on Yersiniabactin and Its Known and Novel Derivatives
Sign Up to like & getrecommendations! Published in 2020 at "Metabolites"
DOI: 10.3390/metabo10060221
Abstract: The Escherichia coli (E. coli) strains Nissle 1917 (EcN), 83972 and CFT073 are closely related but differ in their phenotypes and pathogenicity. The aim of this study was to compare the metabolome of these strains… read more here.
Keywords: pathogenic coli; closely related; study pathogenic; non pathogenic ... See more keywords
Engineered Cell Line Imaging Assay Differentiates Pathogenic from Non-Pathogenic Bacteria
Sign Up to like & getrecommendations! Published in 2022 at "Pathogens"
DOI: 10.3390/pathogens11020209
Abstract: Cell culture systems have greatly expanded our understanding of how bacterial pathogens target signaling pathways to manipulate the host and cause infection. Advances in genetic engineering have allowed for the creation of fluorescent protein readouts… read more here.
Keywords: cell; pathogenic bacteria; cell line; pathogenic non ... See more keywords