Representativeness of the Index Lymph Node for Total Nodal Basin in Pathologic Response Assessment After Neoadjuvant Checkpoint Inhibitor Therapy in Patients With Stage III Melanoma.
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DOI: 10.1001/jamasurg.2021.7554
Abstract: Importance Neoadjuvant checkpoint inhibition in patients with high-risk stage III melanoma shows high pathologic response rates associated with a durable relapse-free survival. Whether a therapeutic lymph node dissection (TLND) can be safely omitted when a… read more here.
Keywords: pathologic response; tlnd; lymph node; response iln ... See more keywords
Association of Matrix Metalloproteinase 7 Expression With Pathologic Response After Neoadjuvant Treatment in Patients With Resected Pancreatic Ductal Adenocarcinoma.
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DOI: 10.1001/jamasurg.2022.1362
Abstract: Importance The use of neoadjuvant therapy (NAT) in resectable pancreatic ductal adenocarcinoma (PDAC) remains controversial. A favorable pathologic response (complete or marked tumor regression) to NAT is associated with better outcomes in patients with resected… read more here.
Keywords: pathologic response; expression; fna biopsy; biopsy specimens ... See more keywords
Does Neutrophil-to-Lymphocyte Ratio (NLR) Predict Pathologic Response to Neoadjuvant Chemoradiotherapy in Patients with Esophageal Squamous Cell Carcinoma?
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DOI: 10.1007/s12029-020-00445-5
Abstract: Background Neoadjuvant chemoradiotherapy (nCRT), followed by surgery, is the current standard of care for patients with locally advanced esophageal squamous cell carcinoma. However, up to 30% of the patients do not respond to nCRT. Hence,… read more here.
Keywords: response; neoadjuvant chemoradiotherapy; patients esophageal; pathologic response ... See more keywords
Reconciling differences in impact of molecular subtyping on response to cisplatin-based chemotherapy
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DOI: 10.1038/s41467-021-24837-8
Abstract: Predictive biomarkers are urgently required in patients with muscle-invasive bladder cancer to determine which patients will benefit from cisplatin-based chemotherapy (CBC). In their study, Taber et al. used an impressive array of multi-omics platforms to… read more here.
Keywords: response; pathologic response; disease; muc ... See more keywords
Complete pathologic response (pCR) following neoadjuvant pembrolizumab monotherapy in treatment-naive locally advanced, mismatch repair protein-deficient (dMMR) colonic cancer: a case report and literature review
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DOI: 10.1080/0284186x.2022.2054289
Abstract: Alfonso Tan-Garcia , Lai Mun Wang, James Chi-Yong Ngu and Lynne Goh Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore; Pathology Section, Department of Laboratory Medicine, Changi General Hospital, Singapore; Pathology Academic Clinical Programme,… read more here.
Keywords: pathologic response; hospital singapore; pathology; response pcr ... See more keywords
Survival Following Trimodality Therapy in Patients With Locally Advanced Esophagogastric Adenocarcinoma: Does Only a Complete Pathologic Response Matter?
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DOI: 10.1097/sla.0000000000004638
Abstract: OBJECTIVE To evaluate whether pCR exclusively defines major pathologic response to treatment with improved survival. SUMMARY BACKGROUND DATA pCR after trimodality therapy for EAC is infrequent but associated with improved prognosis. Yet most clinical trials… read more here.
Keywords: trimodality therapy; survival; pathologic response;
Diffusion-weighted magnetic resonance imaging for predicting pathologic response to neoadjuvant chemoradiotherapy in esophageal squamous cell cancer.
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DOI: 10.1200/jco.2017.35.15_suppl.e15510
Abstract: e15510Background: Neoadjuvant chemoradiotherapy(nCRT) followed by surgery has became the standard treatment for patients with locally advanced esophageal cancer. However, cumulating data showed that only patients who had a pathologic response to neoadjuvant treatment could benefit… read more here.
Keywords: response neoadjuvant; diffusion; response; neoadjuvant chemoradiotherapy ... See more keywords
Outcomes of Mixed Pathologic Response in Patients with Multiple Colorectal Liver Metastases Treated with Neoadjuvant Chemotherapy and Liver Resection
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DOI: 10.1245/s10434-022-11683-1
Abstract: Pathologic response to preoperative chemotherapy predicts survival in patients with colorectal liver metastases (CLMs) who undergo hepatectomy. In multiple CLMs, mixed pathologic response, wherein tumors exhibit different degrees of treatment response, is possible. We sought… read more here.
Keywords: chemotherapy; response; patients multiple; months respectively ... See more keywords
Development of a model to predict pathologic response to chemotherapy in patients with colorectal liver metastases.
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DOI: 10.21037/jgo-21-82
Abstract: Background Preoperative chemotherapy has widely been used in colorectal cancer liver metastasis (CRLM). Pathological response to chemotherapy is very important in evaluating tumor biology. However, there is still a lack of a non-invasive and accurate… read more here.
Keywords: chemotherapy; response; preoperative chemotherapy; response chemotherapy ... See more keywords