Increased Immune Activation by Pathologic α‐Synuclein in Parkinson's Disease
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DOI: 10.1002/ana.25557
Abstract: Excessive inflammation in the central nervous system (CNS) and the periphery can result in neurodegeneration and parkinsonism. Recent evidence suggests that immune responses in Parkinson disease patients are dysregulated, leading to an increased inflammatory reaction… read more here.
Keywords: increased immune; pathologic synuclein; disease; parkinson disease ... See more keywords
Amelioration of pathologic α-synuclein-induced Parkinson’s disease by irisin
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2204835119
Abstract: Significance Physical exercise is thought to have beneficial effects on the symptoms of Parkinson’s disease (PD). Irisin is an exercise-induced myokine released into the circulation. We therefore tested whether irisin itself could have a beneficial… read more here.
Keywords: irisin; disease irisin; pathologic synuclein; parkinson disease ... See more keywords