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Published in 2019 at "British Journal of Surgery"
DOI: 10.1002/bjs.11324
Abstract: Neoadjuvant chemoradiotherapy (nCRT) for locally advanced rectal cancer may induce a pathological complete response (pCR) but increase surgical morbidity due to radiation‐induced fibrosis. In this study the association between pCR and postoperative surgical morbidity was… read more here.
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Published in 2023 at "Cancer Medicine"
DOI: 10.1002/cam4.5693
Abstract: Patients who do not achieve a pathological complete response (pCR) after neoadjuvant systemic treatment (NST) have a significantly worse prognosis. A reliable predictor of prognosis is required to further subdivide non‐pCR patients. To date, the… read more here.
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Published in 2019 at "General Thoracic and Cardiovascular Surgery"
DOI: 10.1007/s11748-019-01076-9
Abstract: ObjectivesWhen induction therapy followed by surgery for locally advanced non-small cell lung cancer results in pathological complete response, the prognosis is excellent; however, relapses can occur. We analyzed the predictive factors for achieving pathological complete… read more here.
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Published in 2021 at "European journal of cancer"
DOI: 10.1016/j.ejca.2021.01.028
Abstract: PURPOSE The aim of the study was to develop and validate a deep learning radiomic nomogram (DLRN) for preoperatively assessing breast cancer pathological complete response (pCR) after neoadjuvant chemotherapy (NAC) based on the pre- and… read more here.
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Published in 2017 at "Lung cancer"
DOI: 10.1016/j.lungcan.2017.07.010
Abstract: A small proportion of patients with malignant pleural mesothelioma (MPM) achieve pathological complete response (CR) following treatment with current practice induction chemotherapy. Our analysis of 58 patients with MPM treated with platinum-based chemotherapy showed 4… read more here.
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Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-51335-1
Abstract: We developed a test to predict which patients will achieve pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) and which will have residual disease (RD). Gene expression data from pretreatment biopsies of patients with all… read more here.
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Published in 2017 at "Medicine"
DOI: 10.1097/md.0000000000009384
Abstract: Background: A pathological complete response (pCR) after neoadjuvant chemotherapy (NCT) is a strong indicator of the benefit of therapy and presents an early surrogate for a favorable long-term outcome. It remains unclear whether Ki-67, a… read more here.
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Published in 2018 at "Medicine"
DOI: 10.1097/md.0000000000012901
Abstract: Background: Although the trends of colorectal incidence rate and mortality have decreased during the past 20 years, however, they are still high. Neoadjuvant chemoradiotherapy is recommended as the standard treatment strategy of local advanced rectal… read more here.
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Published in 2020 at "Journal of Computer Assisted Tomography"
DOI: 10.1097/rct.0000000000000978
Abstract: Objective The objective of this study was to develop a nomogrom for prediction of pathological complete response (PCR) to neoadjuvant chemotherapy in breast cancer patients. Methods Ninety-one patients were analyzed. A total of 396 radiomics… read more here.
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Published in 2022 at "IEEE Journal of Biomedical and Health Informatics"
DOI: 10.1109/jbhi.2022.3216031
Abstract: Neoadjuvant chemotherapy (NAC) is the primary method to reduce the burden of tumor and metastasis; in the treatment of breast cancer, it may provide additional opportunities for breast-conserving surgery. Preoperative assessment of pathological complete response… read more here.
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Published in 2021 at "ANZ Journal of Surgery"
DOI: 10.1111/ans.16665
Abstract: There is a scarcity of data about patients with pancreatic ductal adenocarcinoma (PDAC) who received neoadjuvant therapy before radical resection and achieved a pathological complete response (pCR). The aim of this study was to describe… read more here.