ALKBH3‐Mediated M1A Demethylation of METTL3 Endows Pathological Fibrosis:Interplay Between M1A and M6A RNA Methylation
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DOI: 10.1002/advs.202417067
Abstract: Epigenetic modifications serve as crucial molecular switches for pathological fibrosis; howbeit the role of m1A in this condition remains enigmatic. Herein, it is found that ALKBH3 exerts a pro‐fibrotic effect in pathological skin fibrosis by… read more here.
Keywords: methylation; mettl3; m1a; rna ... See more keywords
Regulation of cardiac fibroblast-mediated maladaptive ventricular remodeling by β-arrestins
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DOI: 10.1371/journal.pone.0219011
Abstract: Cardiac fibroblasts (CF) play a critical role in post-infarction remodeling which can ultimately lead to pathological fibrosis and heart failure. Recent evidence demonstrates that remote (non-infarct) territory fibrosis is a major mechanism for ventricular dysfunction… read more here.
Keywords: biology; collagen synthesis; post; regulation cardiac ... See more keywords