HA of H1N1 enhanced the expression of ICAM-1 and IL-6 in HUVECs and pathological injury in the lungs in mice
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DOI: 10.1016/j.gene.2021.145854
Abstract: Objective Both COVID-19 and influenza are viral respiratory tract infections and the epidemics of viral respiratory tract infections remain highly prevalent with lethal consequences in susceptible individuals. Expression of ICAM-1 on vascular endothelium recruits leukocytes… read more here.
Keywords: injury lungs; expression icam; icam; pathological injury ... See more keywords
NLRP3/caspase-1/GSDMD–mediated pyroptosis exerts a crucial role in astrocyte pathological injury in mouse model of depression
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DOI: 10.1172/jci.insight.146852
Abstract: Emerging evidence suggests that astrocyte loss is one of the most important pathological features in the hippocampus of patients with major depressive disorder (MDD) and depressive mice. Pyroptosis is a recently discovered form of programmed… read more here.
Keywords: gsdmd mediated; gsdmd; pyroptosis; pathological injury ... See more keywords