Stimulation of synaptic activity promotes TFEB-mediated clearance of pathological MAPT/Tau in cellular and mouse models of tauopathies
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DOI: 10.1080/15548627.2022.2095791
Abstract: ABSTRACT Synapses represent an important target of Alzheimer disease (AD), and alterations of their excitability are among the earliest changes associated with AD development. Synaptic activation has been shown to be protective in models of… read more here.
Keywords: mapt tau; activity; stimulation; pathological mapt ... See more keywords