Carbon Dots in the Pathological Microenvironment: ROS Producers or Scavengers?
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202402108
Abstract: Reactive oxygen species (ROS), as metabolic byproducts, play pivotal role in physiological and pathological processes. Recently, studies on the regulation of ROS levels for disease treatments have attracted extensive attention, mainly involving the ROS‐induced toxicity… read more here.
Keywords: ros; ros producers; carbon dots; ros modulating ... See more keywords
Pathological Microenvironment‐Remodeling Nanoparticles to Alleviate Liver Fibrosis: Reversing Hepatocytes‐Hepatic Stellate Cells Malignant Crosstalk (Adv. Sci. 4/2025)
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202570021
Abstract: Liver Fibrosis The cover image depicts an ancient mythology ‘Battle of Zhuolu’. Equipped with sharp weapon (anti‐TGFβ and anti‐ROS), Emperor Yan (hepatic stellate cells) cooperated with Emperor Huang (hepatocytes), defeated Chiyou (liver fibrosis) together and… read more here.
Keywords: fibrosis; stellate cells; liver fibrosis; pathological microenvironment ... See more keywords
Physiologically Inspired Mucin Coated Escherichia coli Nissle 1917 Enhances Biotherapy by Regulating the Pathological Microenvironment to Improve Intestinal Colonization.
Sign Up to like & getrecommendations! Published in 2022 at "ACS nano"
DOI: 10.1021/acsnano.1c09681
Abstract: The delivery of probiotics to the microbiota is a promising method to prevent and treat diseases. However, oral probiotics will suffer from gastrointestinal insults, especially the pathological microenvironment of inflammatory diseases such as reactive oxygen… read more here.
Keywords: regulating pathological; pathological microenvironment; mucin coated; colonization ... See more keywords
Directional Biomimetic Scaffold-Mediated Cell Migration and Pathological Microenvironment Regulation Accelerate Diabetic Bone Defect Repair.
Sign Up to like & getrecommendations! Published in 2025 at "ACS nano"
DOI: 10.1021/acsnano.5c08238
Abstract: Hyperglycemia-induced oxidative stress and inflammation critically impair diabetic bone defect repair. Here, a radially oriented microchannel scaffold (D-GSH@QZ) was developed via a directional freezing technique integrated with photo-cross-linking strategies. The scaffold was fabricated from gelatin… read more here.
Keywords: repair; pathological microenvironment; bone; bone defect ... See more keywords
How the Pathological Microenvironment Affects the Behavior of Mesenchymal Stem Cells in the Idiopathic Pulmonary Fibrosis
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21218140
Abstract: Idiopathic pulmonary fibrosis (IPF) is a chronic disease characterized by fibroblasts activation, ECM accumulation, and diffused alveolar inflammation. The role of inflammation in IPF is still controversial and its involvement may follow nontraditional mechanisms. It… read more here.
Keywords: pathological microenvironment; microenvironment; idiopathic pulmonary; pulmonary fibrosis ... See more keywords