Therapeutic and pathological roles of fibroblast growth factors in pulmonary diseases
Sign Up to like & getrecommendations! Published in 2017 at "Developmental Dynamics"
DOI: 10.1002/dvdy.24468
Abstract: Fibroblast growth factors (FGFs) constitute a large family of polypeptides that are involved in many biological processes, ranging from prenatal cell‐fate specification and organogenesis to hormonal and metabolic regulation in postnatal life. During embryonic development,… read more here.
Keywords: pathological roles; fibroblast growth; growth factors; therapeutic pathological ... See more keywords
Emerging physiological and pathological roles of MeCP2 in non-neurological systems.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2021.108768
Abstract: Numerous neurological and non-neurological disorders are associated with dysfunction of epigenetic modulators, and methyl CpG binding protein 2 (MeCP2) is one of such proteins. Initially identified as a transcriptional repressor, MeCP2 specifically binds to methylated… read more here.
Keywords: emerging physiological; non neurological; physiological pathological; pathological roles ... See more keywords
Pathological Roles for Endothelial Colony Forming Cells in Neonatal and Adult Lung Disease.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of respiratory cell and molecular biology"
DOI: 10.1165/rcmb.2022-0318ps
Abstract: Endothelial colony forming cells (ECFCs) are vascular resident and circulating endothelial cell subtypes with potent angiogenic capacity, a hierarchy of single-cell clonogenic potentials, and the ability to participate in de novo blood vessel formation and… read more here.
Keywords: colony forming; adult; pathological roles; neonatal adult ... See more keywords
Functional and Pathological Roles of AHCY
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.654344
Abstract: Adenosylhomocysteinase (AHCY) is a unique enzyme and one of the most conserved proteins in living organisms. AHCY catalyzes the reversible break of S-adenosylhomocysteine (SAH), the by-product and a potent inhibitor of methyltransferases activity. In mammals,… read more here.
Keywords: functional pathological; roles ahcy; pathological roles; biology ... See more keywords
Physiological and pathological roles of Ang II and Ang- (1-7) in the female reproductive system
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.1080285
Abstract: The local Renin-Angiotensin System (RAS) has been demonstrated to exist in a wide range of tissues and organs, In the female reproductive system, it is mainly found in the ovary, uterus and placenta. The RAS… read more here.
Keywords: system; female reproductive; pathological roles; reproductive system ... See more keywords
Editorial: Beneficial and pathological roles of myeloid cells during COVID-19
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1194826
Abstract: COPYRIGHT © 2023 Sharma, Sengupta and Roger. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided… read more here.
Keywords: pathological roles; editorial beneficial; myeloid cells; cells covid ... See more keywords
Updated Insight into the Physiological and Pathological Roles of the Retromer Complex
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms18081601
Abstract: Retromer complexes mediate protein trafficking from the endosomes to the trans-Golgi network (TGN) or through direct recycling to the plasma membrane. In yeast, they consist of a conserved trimer of the cargo selective complex (CSC),… read more here.
Keywords: physiological pathological; retromer complex; insight physiological; pathological roles ... See more keywords
Mechanisms of Pannexin 1 (PANX1) Channel Mechanosensitivity and Its Pathological Roles
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23031523
Abstract: Pannexins (PANX) were cloned based on their sequence homology to innexins (Inx), invertebrate gap junction proteins. Although there is no sequence homology between PANX and connexins (Cx), these proteins exhibit similar configurations. The PANX family… read more here.
Keywords: channel mechanosensitivity; pathological roles; panx1; mechanisms pannexin ... See more keywords
Emerging Evidence of Pathological Roles of Very-Low-Density Lipoprotein (VLDL)
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23084300
Abstract: Embraced with apolipoproteins (Apo) B and Apo E, triglyceride-enriched very-low-density lipoprotein (VLDL) is secreted by the liver into circulation, mainly during post-meal hours. Here, we present a brief review of the physiological role of VLDL… read more here.
Keywords: emerging evidence; pathological roles; vldl; low density ... See more keywords
Neutrophil Extracellular Traps in Airway Diseases: Pathological Roles and Therapeutic Implications
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24055034
Abstract: Neutrophils are important effector cells of the innate immune response that fight pathogens by phagocytosis and degranulation. Neutrophil extracellular traps (NETs) are released into the extracellular space to defend against invading pathogens. Although NETs play… read more here.
Keywords: traps airway; extracellular traps; pathological roles; neutrophil extracellular ... See more keywords
Physiological and Pathological Roles of Aldose Reductase
Sign Up to like & getrecommendations! Published in 2021 at "Metabolites"
DOI: 10.3390/metabo11100655
Abstract: Aldose reductase (AR) is an aldo-keto reductase that catalyzes the first step in the polyol pathway which converts glucose to sorbitol. Under normal glucose homeostasis the pathway represents a minor route of glucose metabolism that… read more here.
Keywords: polyol pathway; physiological pathological; aldose reductase; pathological roles ... See more keywords