Oral (−)-Epicatechin Inhibits Progressive Tau Pathology in rTg4510 Mice Independent of Direct Actions at GSK3β
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DOI: 10.3389/fnins.2021.697319
Abstract: Aggregation of the microtubule-associated protein tau into paired helical filaments (PHFs) and neurofibrillary tangles is a defining characteristic of Alzheimer’s Disease. Various plant polyphenols disrupt tau aggregation in vitro but display poor bioavailability and low… read more here.
Keywords: pathology rtg4510; rtg4510 mice; tau pathology; pathology ... See more keywords