Gitelman syndrome: an analysis of the underlying pathophysiologic mechanisms of acid–base and electrolyte abnormalities
Sign Up to like & getrecommendations! Published in 2017 at "International Urology and Nephrology"
DOI: 10.1007/s11255-017-1653-4
Abstract: Gitelman syndrome is the most common inherited tubular disease resulting from mutations of the SLC12A3 gene that encodes the thiazide-sensitive sodium–chloride cotransporter in the early distal convoluted tubules. The review presents the underlying pathophysiologic mechanisms… read more here.
Keywords: base electrolyte; underlying pathophysiologic; mechanisms acid; acid base ... See more keywords
Cutaneous Manifestations in Patients With COVID-19: Clinical Characteristics and Possible Pathophysiologic Mechanisms.
Sign Up to like & getrecommendations! Published in 2020 at "Actas dermo-sifiliograficas"
DOI: 10.1016/j.ad.2020.11.013
Abstract: The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections soon led to a pandemic with serious health, economic, political, and cultural repercussions across the globe. The disease caused by SARS-CoV-2, coronavirus disease… read more here.
Keywords: cutaneous manifestations; covid clinical; pathophysiologic mechanisms; manifestations patients ... See more keywords
Oxidative Stress and Acute Kidney Injury in Critical Illness: Pathophysiologic Mechanisms—Biomarkers—Interventions, and Future Perspectives
Sign Up to like & getrecommendations! Published in 2017 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2017/6193694
Abstract: Acute kidney injury (AKI) is a multifactorial entity that occurs in a variety of clinical settings. Although AKI is not a usual reason for intensive care unit (ICU) admission, it often complicates critically ill patients'… read more here.
Keywords: kidney injury; pathophysiologic mechanisms; acute kidney; stress ... See more keywords
The Role of Macrophages in Atherosclerosis: Pathophysiologic Mechanisms and Treatment Considerations
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DOI: 10.3390/ijms24119568
Abstract: Atherosclerotic diseases are a leading cause of morbidity and mortality worldwide, despite the recent diagnostic and therapeutic advances. A thorough understanding of the pathophysiologic mechanisms is thus essential to improve the care of affected individuals.… read more here.
Keywords: pathophysiologic mechanisms; mechanisms treatment; atherosclerosis pathophysiologic; role ... See more keywords
The Therapeutic Role of SGLT-2 Inhibitors in Acute Heart Failure: From Pathophysiologic Mechanisms to Clinical Evidence with Pooled Analysis of Relevant Studies across Safety and Efficacy Endpoints of Interest
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12122062
Abstract: (1) Background: Sodium-glucose co-transporter-2 (SGLT-2) inhibitors constitute a novel drug class with remarkable cardiovascular benefits for patients with chronic heart failure (HF). Recently, this class has been utilized in acute HF as an additional treatment… read more here.
Keywords: pathophysiologic mechanisms; heart failure; sglt inhibitors; relevant studies ... See more keywords