Articles with "pathophysiological implications" as a keyword



Cholesterol Sulfate: Pathophysiological Implications and Potential Therapeutics

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Published in 2025 at "Biomolecules"

DOI: 10.3390/biom15050646

Abstract: Cholesterol sulfate (CS) is a naturally occurring cholesterol derivative that is widely distributed across various tissues and body fluids. In humans, its biosynthesis is primarily mediated by the sulfotransferase (SULT) 2B1b (SULT2B1b). Over the years,… read more here.

Keywords: pathophysiological implications; cholesterol sulfate; metabolism; sulfate pathophysiological ... See more keywords

Aquaporins in Biliary Function: Pathophysiological Implications and Therapeutic Targeting

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Published in 2024 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms252212133

Abstract: Aquaporins (AQPs) are transmembrane proteins permeable to water and a series of small solutes. AQPs play a key role in pathways of hepatobiliary secretion at the level of the liver, bile ducts, and gallbladder. AQP8… read more here.

Keywords: pathophysiological implications; function; aquaporins biliary; water ... See more keywords