Articles with "pathophysiological mechanisms" as a keyword



Sex‐related pathophysiological mechanisms may be present before symptoms of HFpEF develop

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Published in 2025 at "ESC Heart Failure"

DOI: 10.1002/ehf2.15228

Abstract: Understanding sex‐related cardiovascular differences in those with pre‐HFpEF (asymptomatic with normal ejection fraction, elevated natriuretic peptides and structural or functional heart disease) could help explain why females are more likely to develop symptomatic HFpEF compared… read more here.

Keywords: may present; pathophysiological mechanisms; sex; mechanisms may ... See more keywords

Vascular pathologies in chronic kidney disease: pathophysiological mechanisms and novel therapeutic approaches.

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Published in 2021 at "Journal of molecular medicine"

DOI: 10.1007/s00109-021-02037-7

Abstract: Cardiovascular disease (CVD) is a major cause of death in patients with chronic kidney disease (CKD). Both conditions are rising in incidence as well as prevalence, creating poor outcomes for patients and high healthcare costs.… read more here.

Keywords: chronic kidney; disease; ckd; pathophysiological mechanisms ... See more keywords

Impact of sepsis on circulating exosomes: pathophysiological mechanisms, biomarker potential, and therapeutic applications.

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Published in 2025 at "International journal of surgery"

DOI: 10.1097/js9.0000000000003129

Abstract: This comprehensive review examines the complex interplay between sepsis and circulating exosomes. Sepsis, characterized by dysregulated host response to infection leading to life-threatening organ dysfunction, remains a significant global health challenge with high mortality rates.… read more here.

Keywords: impact sepsis; sepsis circulating; pathophysiological mechanisms; circulating exosomes ... See more keywords

Persistence of fatigue in the absence of pathophysiological mechanisms in some patients more than 2 years after the original SARS-CoV-2 infection.

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Published in 2025 at "Experimental physiology"

DOI: 10.1113/ep092850

Abstract: Following an acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a substantial percentage of patients report the persistence of debilitating symptoms, often grouped in a syndrome termed 'long COVID'. We sought to identify… read more here.

Keywords: sars cov; years original; pathophysiological mechanisms; persistence ... See more keywords

Application of computational fluid dynamics to investigate pathophysiological mechanisms in exercise-induced laryngeal obstruction.

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Published in 2024 at "Journal of applied physiology"

DOI: 10.1152/japplphysiol.00230.2024

Abstract: The underlying pathophysiological mechanisms of exercise-induced laryngeal obstruction (EILO) remain to be fully established. It is hypothesised that high inspiratory flow rates can exert a force on laryngeal airway wall that contributeto its inward collapse… read more here.

Keywords: induced laryngeal; mechanisms exercise; pathophysiological mechanisms; exercise induced ... See more keywords
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The Pathophysiological Mechanisms and the Quest for Biomarkers in Psoriasis, a Stress-Related Skin Disease

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Published in 2018 at "Disease Markers"

DOI: 10.1155/2018/5823684

Abstract: Psoriasis is a physically, emotionally, and socially invalidating multifactorial disorder, with a significant impact on the patients' quality of life. Stress is one of the leading triggers for psoriasis and has been associated with disease… read more here.

Keywords: mechanisms quest; stress related; disease; psoriasis ... See more keywords

Exosomes in schizophrenia: Pathophysiological mechanisms, biomarkers, and therapeutic targets

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Published in 2022 at "European Psychiatry"

DOI: 10.1192/j.eurpsy.2022.2319

Abstract: Abstract While schizophrenia (SCZ) is a devastating psychiatric disorder that detrimentally affects a significant portion of the worldwide population, its diagnosis is traditionally based on a relatively subjective assessment of current symptoms and medical history,… read more here.

Keywords: exosomes schizophrenia; mechanisms biomarkers; pathophysiological mechanisms; schizophrenia pathophysiological ... See more keywords

Molecular and pathophysiological mechanisms of diabetic retinopathy in relation to adhesion molecules.

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Published in 2018 at "Current diabetes reviews"

DOI: 10.2174/1573399814666181017103844

Abstract: Diabetic retinopathy (DR) is considered as most common microvascular complication of diabetes affected by one in three people who are suffered for diabetes. Several pathophysiological mechanisms and adhesion molecules may play an etiologic role in… read more here.

Keywords: diabetic retinopathy; adhesion molecules; adhesion; molecular pathophysiological ... See more keywords

Modern concepts of the role of fine particles (PM 2.5) in the genesis of atherosclerosis and myocardial damage: clinical and epidemiological data, the main pathophysiological mechanisms.

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Published in 2022 at "Current cardiology reviews"

DOI: 10.2174/1573403x18666220817103105

Abstract: Due to the fact that atherosclerotic cardiovascular diseases (CVDs) dominate in the structure of morbidity, disability and mortality of the population, the study of the risk factors for the development of atherosclerotic CVDs, as well… read more here.

Keywords: damage; myocardial damage; clinical epidemiological; epidemiological data ... See more keywords
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Pathophysiological mechanisms and clinical evidence of relationship between Nonalcoholic fatty liver disease (NAFLD) and cardiovascular disease.

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Published in 2021 at "Reviews in cardiovascular medicine"

DOI: 10.31083/j.rcm2203082

Abstract: Evidence suggests a close connection between Nonalcoholic Fatty Liver Disease (NAFLD) and increased cardiovascular (CV) risk. Several cross-sectional studies report that NAFLD is related to preclinical atherosclerotic damage, and to coronary, cerebral and peripheral vascular… read more here.

Keywords: fatty liver; pathophysiological mechanisms; disease; disease nafld ... See more keywords

The pathophysiological mechanisms underlying diabetic retinopathy

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Published in 2022 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2022.963615

Abstract: Diabetic retinopathy (DR) is the most common complication of diabetes mellitus (DM), which can lead to visual impairment and even blindness in severe cases. DR is generally considered to be a microvascular disease but its… read more here.

Keywords: underlying diabetic; development; mechanisms underlying; pathophysiological mechanisms ... See more keywords