The pathophysiological role of inflammatory parameters in patients with varicocele.
Sign Up to like & getrecommendations! Published in 2022 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202209_29756
Abstract: OBJECTIVE Varicocele is the abnormal enlargement of the pampiniform plexus in the scrotum and is one of the diseases that have negative consequences on reproduction in men today. The aim of this study is to… read more here.
Keywords: inflammatory parameters; role inflammatory; inflammatory; parameters patients ... See more keywords
Pathophysiological Role of Histamine H4 Receptor in Cancer: Therapeutic Implications
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2019.00556
Abstract: Cancer is a leading cause of death in both developed and developing countries. Although advances in cancer research lead to improved anti-neoplastic therapies, they continue to have unfavorable outcomes, including poor response and severe toxicity.… read more here.
Keywords: h4r; pharmacology; pathophysiological role; cancer ... See more keywords
Pathophysiological Role of Synovitis in Hemophilic Arthropathy Development: A Two-Hit Hypothesis
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2020.00541
Abstract: Despite an increasing access to prophylaxis with clotting factor concentrates, arthropathy still represents the main chronic complication of hemophilia. Whereas previous studies described hemophilic arthropathy (HA) as a degenerative arthropathy, somehow resembling osteoarthritis (OA), most… read more here.
Keywords: hit; role synovitis; hemophilic arthropathy; pathophysiological role ... See more keywords
Pathophysiological Role of Genetic Factors Associated With Gestational Diabetes Mellitus
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.769924
Abstract: Gestational Diabetes Mellitus (GDM) is a highly prevalent maternal pathology characterized by maternal glucose intolerance during pregnancy that is, associated with severe complications for both mother and offspring. Several risk factors have been related to… read more here.
Keywords: role genetic; factors associated; gestational diabetes; genetic factors ... See more keywords
Pathophysiological Role and Diagnostic Potential of R-Loops in Cancer and Beyond
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13122181
Abstract: R-loops are DNA–RNA hybrids that play multifunctional roles in gene regulation, including replication, transcription, transcription–replication collision, epigenetics, and preserving the integrity of the genome. The aberrant formation and accumulation of unscheduled R-loops can disrupt gene… read more here.
Keywords: potential loops; role; diagnostic potential; loops cancer ... See more keywords
The Pathophysiological Role of Thymosin β4 in the Kidney Glomerulus
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24097684
Abstract: Diseases affecting the glomerulus, the filtration unit of the kidney, are a major cause of chronic kidney disease. Glomerular disease is characterised by injury of glomerular cells and is often accompanied by an inflammatory response… read more here.
Keywords: disease; kidney; pathophysiological role; role thymosin ... See more keywords
Pathophysiological Role of Vitamin D Deficiency in Down Syndrome: Insights into Metabolic Dysfunction and Sarcopenia
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms262110756
Abstract: People with Down syndrome represent a highly vulnerable population, frequently showing vitamin D deficiency together with an elevated risk of metabolic and neuromuscular dysfunction. This susceptibility derives from several factors, including muscular hypotonia, excess body… read more here.
Keywords: pathophysiological role; muscle; vitamin deficiency; dysfunction ... See more keywords